Synthesis of bivalent neogalactolipids via modified Staudinger reaction

被引：3
|
作者：
Ivanova, Ekaterina A. [1 ]
Maslov, Mikhail A. [1 ]
Morozova, Nina G. [1 ]
Serebrennikova, Galina A. [1 ]
Chupin, Vladimir V. [1 ,2 ]
机构：
[1] MV Lomonosov Moscow State Univ Fine Chem Technol, Moscow, Russia
[2] Shemyakin Ovchinnikov Inst Bioorgan Chem RAS, Moscow, Russia
来源：
RSC ADVANCES | 2012年 / 2卷 / 11期
关键词：
ASIALOGLYCOPROTEIN RECEPTOR; GENE DELIVERY; PROTEINS; IMMOBILIZATION; LECTIN;
D O I：
10.1039/c2ra01356h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of bivalent galactose-containing neutral lipids for the development of a targeted gene delivery system to the hepatocytes has been described. For introducing galactosyl ligands into the lipid molecule, a convenient approach based on modified Staudinger reaction was used.
引用
收藏
页码：4600 / 4602
页数：3
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