Synthesis of bivalent neogalactolipids via modified Staudinger reaction

被引：3

作者：

Ivanova, Ekaterina A. ^{[1
]}

Maslov, Mikhail A. ^{[1
]}

Morozova, Nina G. ^{[1
]}

Serebrennikova, Galina A. ^{[1
]}

Chupin, Vladimir V. ^{[1
,2
]}

机构：

[1] MV Lomonosov Moscow State Univ Fine Chem Technol, Moscow, Russia

[2] Shemyakin Ovchinnikov Inst Bioorgan Chem RAS, Moscow, Russia

来源：

RSC ADVANCES | 2012年 / 2卷 / 11期

关键词：

ASIALOGLYCOPROTEIN RECEPTOR; GENE DELIVERY; PROTEINS; IMMOBILIZATION; LECTIN;

D O I：

10.1039/c2ra01356h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of bivalent galactose-containing neutral lipids for the development of a targeted gene delivery system to the hepatocytes has been described. For introducing galactosyl ligands into the lipid molecule, a convenient approach based on modified Staudinger reaction was used.

引用

页码：4600 / 4602

页数：3

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