Efficient synthesis of sugar iminopyrrolidine derivatives via an intramolecular Staudinger-aza-Wittig-type reaction

被引：8
|
作者：
Ducatel, Helene
Van Nhien, Albert Nguyen
Pilard, Serge
Postel, Denis
机构：
[1] Univ Picardie, Fac Sci, UMR 6219, Lab Glucides, F-80039 Amiens, France
[2] Univ Picardie, Fac Sci, Plateforme Analyt, F-80039 Amiens, France
来源：
SYNLETT | 2006年 / 12期
关键词：
aza-sugars; Wittig reactions; glycoamino nitrile; glycoamino acids; iNOS;
D O I：
10.1055/s-2006-948177
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We report herein the first example of a Staudinger-azaWittig-type reaction on a substituted furanoside in which a beta-azido glyco-alpha-aminonitrile was converted into fused iminopyrrolidines in good yields, and the following hydrolysis gave the corresponding conformationally restricted glycoamino acids.
引用
收藏
页码：1875 / 1878
页数：4
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