Association between bleomycin hydrolase and Alzheimer's disease in Caucasians

被引：34

作者：

Farrer, LA

Abraham, CR

Haines, JL

Rogaeva, EA

Song, YQ

McGraw, WT

Brindle, N

Premkumar, S

Scott, WK

Yamaoka, LH

Saunders, AM

Roses, AD

Auerbach, SA

Sorbi, S

Duara, R

Pericak-Vance, MA

St George-Hyslop, PH

机构：

[1] Boston Univ, Sch Med, Genet Program, Dept Med, Boston, MA 02118 USA

[2] Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA

[3] Boston Univ, Sch Med, Dept Epidemiol & Biostat, Boston, MA 02118 USA

[4] Boston Univ, Sch Med, Dept Biochem, Boston, MA 02118 USA

[5] Vanderbilt Univ, Program Human Genet, Nashville, TN USA

[6] Univ Toronto, Ctr Res Neurodegenerat Dis, Toronto, ON, Canada

[7] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA

[8] Univ Florence, Dept Neurol, Florence, Italy

[9] Univ Florence, Dept Psychiat, Florence, Italy

[10] Mt Sinai Med Ctr, Wien Ctr, Dept Neurol, Miami, FL USA

来源：

ANNALS OF NEUROLOGY | 1998年 / 44卷 / 05期

关键词：

D O I：

10.1002/ana.410440515

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A recent study showed modest evidence for an increased frequency of the bleomycin hydrolase (BH) VN genotype in Alzheimer's disease (AD) patients compared with nondemented controls. To test this hypothesis, we examined this polymorphism in 621 rigorously evaluated patients and 502 control subjects (all caucasian) but were unable to detect an association between BH and AD even after controlling for age, gender, and apolipoprotein E (ApoE) genotype. We conclude that this polymorphism does not account for inherited susceptibility to AD in the populations represented in this sample.

引用

页码：808 / 811

页数：4

共 50 条

[21] Regional and cellular distribution of bleomycin hydrolase mRNA in human brain: comparison between Alzheimer's diseased and control brains
Malherbe, P
Faull, RLM
Richards, JG
NEUROSCIENCE LETTERS, 2000, 281 (01) : 37 - 40
[22] Association of UBQ-8i polymorphism with Alzheimer's disease in Caucasians: a meta-analysis
Yue, Zhen
Wang, Sen
Yan, Weiping
Zhu, Fengyi
INTERNATIONAL JOURNAL OF NEUROSCIENCE, 2015, 125 (06) : 395 - 401
[23] Association between Cytokine Production and Disease Severity in Alzheimer's Disease
Azad, Farahzad Jabbari
Talaei, Ali
Rafatpanah, Houshang
Yousefzadeh, Hadis
Jafari, Rahele
Jafari, Majid
Talaei, Andisheh
Hosseini, Reza Farid
IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY, 2014, 13 (06) : 433 - 439
[24] Association between chronic kidney disease and Alzheimer’s disease: an update
Chun-Yun Zhang
Fang-Fang He
Hua Su
Chun Zhang
Xian-Fang Meng
Metabolic Brain Disease, 2020, 35 : 883 - 894
[25] Association between chronic kidney disease and Alzheimer's disease: an update
Zhang, Chun-Yun
He, Fang-Fang
Su, Hua
Zhang, Chun
Meng, Xian-Fang
METABOLIC BRAIN DISEASE, 2020, 35 (06) : 883 - 894
[26] No association between very low density lipoprotein receptor (VLDL-R) and Alzheimer disease in American Caucasians
Pritchard, ML
Saunders, AM
Gaskell, PC
Small, GW
Conneally, PM
Rosi, B
Yamaoka, LH
Roses, AD
Haines, JL
PericakVance, MA
NEUROSCIENCE LETTERS, 1996, 209 (02) : 105 - 108
[27] The association between APOE genotype and progression of Alzheimer's disease
Tsolaki, M.
Bosiki, M.
Daniilidou, M.
Pitsalidis, C. H.
Molyva, D.
Kounti, F.
Papassotiropoulos, A.
Kazis, A.
EUROPEAN JOURNAL OF NEUROLOGY, 2005, 12 : 58 - 58
[28] Association between periodontitis and Alzheimer's disease: A narrative review
Seyedmoalemi, Mohammad Amin
Saied-Moallemi, Zahra
IBRO NEUROSCIENCE REPORTS, 2025, 18 : 360 - 365
[29] Association between neuropsychiatric and autonomic dysfunction in Alzheimer's disease
Juan Idiaquez
Eduardo Sandoval
Alejandra Seguel
Clinical Autonomic Research, 2002, 12 : 43 - 46
[30] Association Between Lithium Use and Risk of Alzheimer's Disease
Cheng, Chin
Zandi, Peter
Stuart, Elizabeth
Lin, Ching-Heng
Su, Pei-Yu
Alexander, G. Caleb
Lan, Tsuo-Hung
JOURNAL OF CLINICAL PSYCHIATRY, 2017, 78 (02) : E139 - +

← 1 2 3 4 5 →