Sequential and domino Sonogashira coupling:: Efficient tools for the synthesis of diarylalkynes

被引：37
|
作者：
Nagy, A [1 ]
Novák, Z [1 ]
Kotschy, A [1 ]
机构：
[1] Eotvos Lorand Univ, Dept Gen & Inorgan Chem, H-1117 Budapest, Hungary
来源：
JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2005年 / 690卷 / 20期
关键词：
Sonogashira reaction; cross-coupling; diarylalkynes; palladium;
D O I：
10.1016/j.jorganchem.2004.12.036
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The Sonogashira, coupling reaction of aryl halides with a masked acetylene, leading to the formation of diarylethynes is reviewed. The process is either run in a sequential coupling-deprotection-coupling manner, or sometimes it is carried out in one-pot, a reaction we coined domino coupling. The procedures were also extended to the synthesis Of Compound libraries. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码：4453 / 4461
页数：9
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