Synthesis of diarylalkynes via tandem Sonogashira/decarboxylative reaction of aryl chlorides with propiolic acid

被引：24
|
作者：
Li, Xiang [1 ]
Yang, Fan [1 ]
Wu, Yangjie [1 ]
机构：
[1] Zhengzhou Univ, Key Lab Appl Chem Henan Univ, Henan Key Lab Chem Biol & Organ Chem, Coll Chem & Mol Engn, Zhengzhou 450052, Peoples R China
来源：
RSC ADVANCES | 2014年 / 4卷 / 26期
关键词：
ALKYNYL CARBOXYLIC-ACIDS; CROSS-COUPLING REACTIONS; ONE-POT SYNTHESIS; SONOGASHIRA REACTION; COPPER-FREE; TERMINAL ACETYLENES; EFFICIENT SYNTHESIS; AMINE-FREE; HALIDES; CARBON;
D O I：
10.1039/c3ra47712f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A facile and efficient protocol for one-pot synthesis of diarylalkynes via tandem Sonogashira/decarboxylative coupling has been developed. The remarkable features of this reaction include using commercially available aryl chlorides as starting materials and taking the propiolic acid instead of expensive terminal alkynes as an acetylene source.
引用
收藏
页码：13738 / 13741
页数：4
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