One-pot synthesis of diarylalkynes using palladium-catalyzed Sonogashira reaction and decarboxylative coupling of sp carbon and sp2 carbon

被引：268
|
作者：
Moon, Jeongju [1 ]
Jeong, Miso [1 ]
Nam, Hyungoog [1 ]
Ju, Jinhun [1 ]
Moon, Joong Ho [2 ]
Jung, Hyun Min [3 ]
Lee, Sunwoo [1 ]
机构：
[1] Chonnam Natl Univ, Dept Chem, Kwangju 500757, South Korea
[2] ICx Nomad Inc, Cambridge, MA 02142 USA
[3] Korea Res Inst Chem Technol, Adv Mat Div, Taejon 305600, South Korea
来源：
ORGANIC LETTERS | 2008年 / 10卷 / 05期
关键词：
D O I：
10.1021/ol703130y
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Decarboxylative coupling of sp-sp(2) carbons is possible by palladium catalyst. Employing propiolic acid (1) as a difunctional alkyne, and using the consecutive reactions of the Sonogashira reaction and the decarboxylative coupling, unsymmetrically substituted diaryl alkynes were obtained in moderate to good yield.
引用
收藏
页码：945 / 948
页数：4
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