C(2)-Functionalization of pyrimidin-4(3H)-one derivatives in the synthesis of its biologically active derivatives

被引：4
|
作者：
Novakov, I. A. [1 ]
Navrotskii, M. B. [1 ]
Zakharova, E. K. [1 ]
Brunilina, L. L. [1 ]
机构：
[1] Volgograd State Tech Univ, 28 Prosp Lenina, Volgograd 400131, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 2015年 / 64卷 / 11期
关键词：
isocytosine; uracil; 2-thiouracil; REVERSE-TRANSCRIPTASE INHIBITORS; H2-RECEPTOR HISTAMINE-ANTAGONISTS; IMMUNODEFICIENCY-VIRUS TYPE-1; SELECTIVE ANTI-HIV-1 AGENTS; ANTI-HIV ACTIVITY; ANTITUMOR-ACTIVITY; MKC-442; ANALOGS; PYRIMIDINE-DERIVATIVES; ANTIVIRAL ACTIVITY; 3,4-DIHYDRO-2-ALKOXY-6-BENZYL-4-OXOPYRIMIDINES DABOS;
D O I：
10.1007/s11172-015-1190-1
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Different approaches to the formation of biologically active isocytosine, uracil, and 2-thiouracil derivatives based on the C(2)-regioselective functionalization of pyrimidin-4(3H)-one framework were considered.
引用
收藏
页码：2545 / 2561
页数：17
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