C(2)-Functionalization of pyrimidin-4(3H)-one derivatives in the synthesis of its biologically active derivatives

被引：4

作者：

Novakov, I. A. ^{[1
]}

Navrotskii, M. B. ^{[1
]}

Zakharova, E. K. ^{[1
]}

Brunilina, L. L. ^{[1
]}

机构：

[1] Volgograd State Tech Univ, 28 Prosp Lenina, Volgograd 400131, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2015年 / 64卷 / 11期

关键词：

isocytosine; uracil; 2-thiouracil; REVERSE-TRANSCRIPTASE INHIBITORS; H2-RECEPTOR HISTAMINE-ANTAGONISTS; IMMUNODEFICIENCY-VIRUS TYPE-1; SELECTIVE ANTI-HIV-1 AGENTS; ANTI-HIV ACTIVITY; ANTITUMOR-ACTIVITY; MKC-442; ANALOGS; PYRIMIDINE-DERIVATIVES; ANTIVIRAL ACTIVITY; 3,4-DIHYDRO-2-ALKOXY-6-BENZYL-4-OXOPYRIMIDINES DABOS;

D O I：

10.1007/s11172-015-1190-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Different approaches to the formation of biologically active isocytosine, uracil, and 2-thiouracil derivatives based on the C(2)-regioselective functionalization of pyrimidin-4(3H)-one framework were considered.

引用

页码：2545 / 2561

页数：17

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