Enantioselective addition of diethylzinc to aldehydes in the presence of chiral aprotic ligands

被引：8
|
作者：
Jin, MJ [1 ]
Kim, YM [1 ]
Lee, KS [1 ]
机构：
[1] Inha Univ, Sch Chem Sci & Engn, Inchon 402751, South Korea
来源：
TETRAHEDRON LETTERS | 2005年 / 46卷 / 15期
关键词：
D O I：
10.1016/j.tetlet.2005.02.066
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Optically active amino thiocyanate derivatives of (-)-norephedrine were found to act as effective aprotic ligands for enantioselective addition of diethylzinc to aldehydes. This reaction provided optically active secondary alcohols with ee up to 96%. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2695 / 2696
页数：2
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