Analysis of HLA-G protein expression in leprosy

被引：1

作者：

da Silva, Camila Rodrigues ^{[1
]}

Sampaio, Lucas Henrique Ferreira ^{[2
]}

Costa, Mauricio Barcelos ^{[1
]}

de Paula Carneiro Cysneiros, Maria Auxiliadora ^{[1
]}

Sadissou, Ibrahim Abiodoun ^{[3
]}

de Oliveira Rodrigues Castilho, Mirian Lane ^{[1
]}

de Moraes, Jonathan Ballico ^{[2
]}

Donadi, Eduardo Antonio ^{[3
]}

Wastoswki, Isabela Jube ^{[2
,4
]}

机构：

[1] Univ Fed Goias UFG, Goiania, Go, Brazil

[2] Univ Estadual Goias UEG, Goiania, Go, Brazil

[3] Univ Sao Paulo, Ribeirao Preto, SP, Brazil

[4] Mol Immunol Lab UEG UnU Laranjeiras, Ave Prof Alfredo de Castro S-N, BR-74855130 Goiania, Go, Brazil

来源：

IMMUNOGENETICS | 2020年 / 72卷 / 05期

关键词：

HLA; HLA-G; Leprosy; Immune response;

D O I：

10.1007/s00251-020-01168-4

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The aim of this study was to evaluate the expression of human leukocyte antigen G (HLA-G) in leprosy. Biopsy and serum samples were collected from 18 patients presenting with leprosy and from healthy controls. Samples were analyzed using immunohistochemistry and ELISA techniques. HLA-G expression was observed in biopsy samples of all patients. The healthy control samples were consistently negative for HLA-G expression. Control plasma samples displayed significantly higher HLA-G expression than those from the patients (p < 0.01). These results are the first demonstration of the expression of HLA-G in leprosy.

引用

页码：333 / 337

页数：5

共 50 条

[41] Analysis of the role of HLA-G in preeclampsia
O'Brien, M
Dausset, J
Carosella, ED
Moreau, P
HUMAN IMMUNOLOGY, 2000, 61 (11) : 1126 - 1131
[42] HUMAN LEUCOCYTE ANTIGEN G (HLA-G) EXPRESSION AND HLA-G REGULATORY HAPLOTYPES IN PATIENTS WITH PAPILLARY THYROID CARCINOMA
Bertol, Bruna C.
Goes de Araujo, Jessica Nayara
de Figueiredo-Feitosa, Nathalie L. L.
Collares, Cristhianna V. A.
Conti de Freitas, Luiz C.
Soares, Edson Garcia
Serafini, Luciano Neder
Silbiger, Vivian Nogueira
Zanini Maciel, Lea M.
Donadi, Eduardo A.
HLA, 2020, 95 (04) : 362 - 362
[43] A set of antibodies which specifically bind alternative HLA-G proteins distinguish HLA-G expression in vivo
Ishitani, A
Dorofeeva, N
Lee, N
Kapasi, K
Hunt, J
Geraghty, DE
HUMAN IMMUNOLOGY, 1996, 47 (1-2) : O780 - O780
[44] Associations of HLA-G 3'UTR polymorphisms and increased HLA-G expression with gastric cancer susceptibility and prognosis
Zemni, Ines
Bortolotti, Daria
Dhouioui, Sabrine
Baroudi, Sana
Ferjani, Malek
Nasri, Ines
Zenzri, Yosr
Rahman, Md Ataur
Harrath, Abdel Halim
Rizzo, Roberta
Boujelbene, Nadia
Zidi, Ines
IMMUNOBIOLOGY, 2025, 230 (01)
[45] COMBINED ANALYSIS OF HLA-G AND HLA-E EXPRESSION IN TUNISIAN PATIENTS WITH ENDOMETRIAL CANCER
Ben Yahia, H.
Babay, W.
Boujelbene, N.
Laaribi, A. B.
Touhami, O.
Kacem, D.
Chanoufi, M. B.
Ouzari, I.
Mrad, K.
Rizzo, R.
Zidi, I.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2016, 26 : 1094 - 1094
[46] HLA-G allelic variants are associated with differences in the HLA-G mRNA isoform profile and HLA-G mRNA levels
Hviid, TVF
Hylenius, S
Rorbye, C
Nielsen, LG
TISSUE ANTIGENS, 2003, 62 (04): : 354 - 354
[47] HLA-G allelic variants are associated with differences in the HLA-G mRNA isoform profile and HLA-G mRNA levels
Hviid, TVF
Hylenius, S
Rorbye, C
Nielsen, LG
IMMUNOGENETICS, 2003, 55 (02) : 63 - 79
[48] HLA-G allelic variants are associated with differences in the HLA-G mRNA isoform profile and HLA-G mRNA levels
Thomas Vauvert F. Hviid
Sine Hylenius
Christina Rørbye
Lone G. Nielsen
Immunogenetics, 2003, 55 : 63 - 79
[49] Association of soluble HLA-G plasma levels with HLA-G alleles
Rebmann, V
van der Ven, K
Pässler, M
Pfeiffer, K
Krebs, D
Grosse-Wilde, H
TISSUE ANTIGENS, 2001, 57 (01): : 15 - 21
[50] A novel HLA-G allele, HLA-G*010111, in the Brazilian population
Castelli, E. C.
Mendes, C. T., Jr.
Wiezel, C. E. V.
Peres, N. T. A.
Simoes, A. L.
Rossi, N. M. M.
Donadi, E. A.
TISSUE ANTIGENS, 2007, 70 (04): : 349 - U8

← 1 2 3 4 5 →