Synthesis and biological activity of S-containing betulin derivatives

被引：11
|
作者：
Tolmacheva, IA [1 ]
Shelepen'kina, LN [1 ]
Vikharev, YB [1 ]
Anikina, LV [1 ]
Grishko, VV [1 ]
Tolstikov, AG [1 ]
机构：
[1] Russian Acad Sci, Urals Div, Inst Tech Chem, Perm 614990, Russia
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2005年 / 41卷 / 06期
关键词：
triterpenoids; betulin; sulfides; sulfoxides; anti-inflammatory activity;
D O I：
10.1007/s10600-006-0015-8
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
S-Containing derivatives of the natural triterpenoid betulin were synthesized. It has been found that the 30-thio- and 30-sulfinylbenzinfidazole derivatives of betulin exhibit anti-inflammatory activity comparable to that of sodium diclofenac
引用
收藏
页码：701 / 705
页数：5
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