Synthesis and biological activity of S-containing betulin derivatives

被引：11

作者：

Tolmacheva, IA ^{[1
]}

Shelepen'kina, LN ^{[1
]}

Vikharev, YB ^{[1
]}

Anikina, LV ^{[1
]}

Grishko, VV ^{[1
]}

Tolstikov, AG ^{[1
]}

机构：

[1] Russian Acad Sci, Urals Div, Inst Tech Chem, Perm 614990, Russia

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2005年 / 41卷 / 06期

关键词：

triterpenoids; betulin; sulfides; sulfoxides; anti-inflammatory activity;

D O I：

10.1007/s10600-006-0015-8

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

S-Containing derivatives of the natural triterpenoid betulin were synthesized. It has been found that the 30-thio- and 30-sulfinylbenzinfidazole derivatives of betulin exhibit anti-inflammatory activity comparable to that of sodium diclofenac

引用

页码：701 / 705

页数：5

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