Determination of Clonidine by Potentiometry Using PVC Membrane Electrode

被引：0

作者：

Ganjali, Mohammad Reza ^{[1
,2
]}

Karimi, Anahita ^{[1
]}

Shahtaheri, Sayed Jamaleddin ^{[3
]}

Norouzi, Parviz ^{[1
,2
]}

机构：

[1] Univ Tehran, Ctr Excellence Electrochem, Tehran, Iran

[2] Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran

[3] Univ Tehran Med Sci, Sch Publ Hlth, Dept Occupat Hlth, Environm Res Ctr, Tehran, Iran

来源：

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE | 2013年 / 8卷 / 02期

关键词：

Clonidine; Potentiometric Sensor; PVC membrane Electrode; Ion-Pair; COMPOSITE CARBON-PASTE; ION-SELECTIVE ELECTRODE; PHARMACEUTICAL FORMULATION; LANTHANIDE RECOGNITION; QUANTITATIVE-ANALYSIS; ANION RECOGNITION; SENSING MATERIAL; SENSOR; HYDROCHLORIDE; CONSTRUCTION;

D O I：

暂无

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

PVC membrane potentiometric sensor was made for determination of Clonidine in pharmaceutical formulations. The electrode respond based on ion-exchange mechanism. The ion-pair used as a sensing element in PVC membrane composition was synthesized by interaction of Clonidine hydrochloride and tetraphenyl borate. The best PVC membrane sensor response was obtained by a membrane composition of 30% PVC, 62% DBP, 6% ion-pair and 2% ionic liquid. The proposed method was successfully applied in determination of Clonidine in some formulations. The proposed sensor showed a linear dynamic range between 7.0x10(-6)-1.0x10(-2) M of Clonidine with a Nernstian slope of (58.3+/-0.4) mV decade(-1) and a detection limit of 6.5x10(-6) M. The proposed electrode displayed fast response time about 10 s, and lifetime of about six weeks without any significant change in its performance.

引用

页码：1999 / 2008

页数：10

共 50 条

[1] Determination of lithium by potentiometry using fluoride ion selective electrode
Govindan, R.
Alamelu, D.
Shah, Raju V.
Rao, T. V. Vittal
Bamankar, Y. R.
Parab, A. R.
Bhushan, K. Sasi
Mukerjee, S. K.
Aggarwal, S. K.
ANALYTICAL METHODS, 2010, 2 (11) : 1752 - 1755
[2] A Novel Tetraiodocadmate(Ⅱ)–PVC Membrane Electrode for the Potentiometric Determination of Cadmium(Ⅱ)
Fu Chang WANG
ChineseChemicalLetters, 2006, (07) : 941 - 944
[3] PVC Membrane Sensor and Wire Coated Electrode for Determination of Flurazepam
Norouzi, Parviz
Rashedi, Hamid
Alipour, Aidin
Faridbod, Farnoush
Shahtaheri, S. Jamaleddin
Ganjali, Mohammad Reza
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2011, 6 (07): : 2312 - 2322
[4] BENZYLPENICILLIN PVC MEMBRANE-ELECTRODE FOR THE DETERMINATION OF ANTIBIOTICS IN FORMULATIONS
CAMPANELLA, L
MAZZEI, F
SBRILLI, R
TOMASSETTI, M
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1988, 6 (03) : 299 - 305
[5] Nonselective electrode with plasticized PVC membrane for the determination of Tc(VII)
Dorokhov, A.V.
German, K.E.
Peretrukhin, V.F.
Kopytin, A.V.
Pyatova, E.N.
Burtsev, M.Yu.
Simonoff, M.
Tsivadze, A.Yu.
Doklady Akademii Nauk, 2003, 393 (04) : 501 - 503
[6] Direct determination of triamterene by potentiometry using a coated wire selective electrode
Arvand, M
Mousavi, MF
Zanjanchi, MA
Shamsipur, M
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2003, 33 (05) : 975 - 982
[7] PVC membrane electrode for the potentiometric determination of Ipratropium bromide using batch and flow injection techniques
Hassouna, M. E. M.
Elsuccary, S. A. A.
TALANTA, 2008, 75 (05) : 1175 - 1183
[8] SULFATE DETERMINATION BY MEANS OF POTENTIOMETRY WITH SELECTIVE ELECTRODE
DEMEDINA, HL
GONZALEZ, G
LOBOS, P
INTERCIENCIA, 1994, 19 (01) : 24 - 27
[9] Novel PVC Membrane Selective Electrode for the Determination of Clozapine in Pharmaceutical Preparations
Al Attas, Amirh S.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2009, 4 (01): : 9 - 19
[10] PVC membrane electrode for the direct determination of chlorpheniramine maleate in pharmaceutical preparations
El-Tohamy, Maha
El-Maamly, Magda
Shalaby, Abdalla
ASIAN JOURNAL OF CHEMISTRY, 2007, 19 (04) : 3035 - 3046

← 1 2 3 4 5 →