Approaches to the Syntheses of Partially Reduced Imidazo[1,2-a]pyridines

被引：0

作者：

Shin, Junhwa ^{[1
]}

Nho, Young Chang ^{[1
]}

Howard, Arthur S. ^{[2
]}

机构：

[1] Korea Atom Energy Res Inst, Adv Radiat Technol Inst, Jeongeup 580185, Jeonbuk, South Korea

[2] Eastern Michigan Univ, Dept Chem, Ypsilanti, MI 48179 USA

来源：

BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2008年 / 29卷 / 10期

关键词：

Aza-alkaloid; Heterocyclic compounds; Indolizidine;

D O I：

10.5012/bkcs.2008.29.10.1998

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two synthetic pathways to substituted hexahydroimidazo[1,2-a]pyridines, which may serve as precursors of aza-alkaloids, were investigated. The first involves the condensation of a bisnucleophilic enediaminoester and a biselectrophile. The second involves attachment to nitrogen of the carbon chain skeleton required to form the six-memberd ring, before formation of the enediaminoester. Several substituted hexahydroimidazo[1,2-a]pyridines were synthesized via these two approaches.

引用

页码：1998 / 2004

页数：7

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