Approaches to the Syntheses of Partially Reduced Imidazo[1,2-a]pyridines

被引：0

作者：

Shin, Junhwa ^{[1
]}

Nho, Young Chang ^{[1
]}

Howard, Arthur S. ^{[2
]}

机构：

[1] Korea Atom Energy Res Inst, Adv Radiat Technol Inst, Jeongeup 580185, Jeonbuk, South Korea

[2] Eastern Michigan Univ, Dept Chem, Ypsilanti, MI 48179 USA

来源：

BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2008年 / 29卷 / 10期

关键词：

Aza-alkaloid; Heterocyclic compounds; Indolizidine;

D O I：

10.5012/bkcs.2008.29.10.1998

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two synthetic pathways to substituted hexahydroimidazo[1,2-a]pyridines, which may serve as precursors of aza-alkaloids, were investigated. The first involves the condensation of a bisnucleophilic enediaminoester and a biselectrophile. The second involves attachment to nitrogen of the carbon chain skeleton required to form the six-memberd ring, before formation of the enediaminoester. Several substituted hexahydroimidazo[1,2-a]pyridines were synthesized via these two approaches.

引用

页码：1998 / 2004

页数：7

共 50 条

[21] Synthesis of imidazo[1,2-a]pyridines: a decade update
Bagdi, Avik Kumar
Santra, Sougata
Monir, Kamarul
Hajra, Alakananda
CHEMICAL COMMUNICATIONS, 2015, 51 (09) : 1555 - 1575
[22] SOME SELENIUM DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINES
HAND, ES
PAUDLER, WW
JOURNAL OF ORGANIC CHEMISTRY, 1975, 40 (20): : 2916 - 2920
[23] Substituted Imidazo[1,2-a]pyridines as β-Strand Peptidomimetics
Kang, Chang Won
Sun, Yongmao
Del Valle, Juan R.
ORGANIC LETTERS, 2012, 14 (24) : 6162 - 6165
[24] An efficient synthesis of ferrocenyl imidazo[1,2-a]pyridines
Akbarzadeh, Roya
Shakibaei, Ghazaleh Imani
Bazgir, Ayoob
MONATSHEFTE FUR CHEMIE, 2010, 141 (10): : 1077 - 1081
[25] Sustainable approaches towards the synthesis of functionalized imidazo [1,2-a]pyridines: Recent advancements
Sofi, Firdoos Ahmad
Gogde, Kunal
Mukherjee, Debarupa
Masoodi, Mubashir H.
JOURNAL OF MOLECULAR STRUCTURE, 2024, 1297
[26] Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents
Ismail, MA
Brun, R
Wenzler, T
Tanious, FA
Wilson, WD
Boykin, DW
JOURNAL OF MEDICINAL CHEMISTRY, 2004, 47 (14) : 3658 - 3664
[27] SYNTHESES AND OXIDATIONS OF IMIDAZO [1,2-A] QUINOLINES AND PYRIMIDO [1,2-A] QUINOLINES
KWON, S
ISAGAWA, K
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 1973, 31 (04) : 313 - 321
[28] Synthesis of Partially Reduced Imidazo[1,2-a]pyridines through an Unprecedented Base-Mediated (4+2) Cyclization
Panwar, Rahul
Singh, Surjeet
Yadav, Pratik
Shally
Shaw, Ranjay
Kumar, Abhinav
Pratap, Ramendra
SYNLETT, 2017, 28 (07) : 819 - 824
[29] Thermal cyclization of 1,2-dialkynylimidazoles to imidazo[1,2-a]pyridines
Nadipuram, AK
Kerwin, SM
TETRAHEDRON, 2006, 62 (16) : 3798 - 3808
[30] Synthesis of Imidazo[1,2-a]pyridines and Pyrido[1,2-a]pyrimidines in Water and their SNAr Cyclizations
Chanu, Langpoklakpam Gellina
Singh, Thokchom Prasanta
Jang, Yong Ju
Yoon, Yong-Jin
Singh, Okram Mukherjee
Lee, Sang-Gyeong
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2014, 35 (04): : 994 - 1000

← 1 2 3 4 5 →