Nitrosylation of imidazo[1,2-a] pyridines in metal free system

被引：5
|
作者：
Hao, Xin-Qi [1 ]
Liu, Wen-Bo [1 ]
Shen, Xiao-Jing [1 ]
Wang, Wei [2 ]
Liang, Zhi-Kun [1 ]
Zhu, Xinju [1 ]
Song, Mao-Ping [1 ]
机构：
[1] Zhengzhou Univ, Henan Key Lab Chem Biol & Organ Chem, Coll Chem & Mol Engn, 100 Sci Rd, Zhengzhou 450001, Henan, Peoples R China
[2] North China Univ Water Resources & Elect Power, Dept Environm & Municipal Engn, 1 Jinshui East Rd Longzi Lake, Zhengzhou 450046, Henan, Peoples R China
来源：
JOURNAL OF SAUDI CHEMICAL SOCIETY | 2017年 / 21卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Nitrosylation; Imidazo[1,2-a] pyridines; tert-Butyl nitrite (TBN); Near quantitative yields; DERIVATIVES; INSOMNIA; RECEPTOR; ZOLPIDEM;
D O I：
10.1016/j.jscs.2016.02.004
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient nitrosylation of imidazo[1,2-a] pyridines has been developed using tert-Butyl nitrite (TBN) as the NO resource. The nitrosylation protocol demonstrates broad compatibilities, with various functional groups such as halogen, Me, OMe, COOMe et al. well tolerated. Near quantitative yields could be obtained within the imidazo[1,2-a] pyridine scaffold under the optimized conditions. (C) 2016 King Saud University. Production and hosting by Elsevier B.V.
引用
收藏
页码：91 / 94
页数：4
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