Lipase-mediated resolution of cis-1-amino-2-indanol, the key component of the HIV protease inhibitor indinavir

被引：13

作者：

Anilkumar, AT ^{[1
]}

Goto, K ^{[1
]}

Takahashi, T ^{[1
]}

Ishizaki, K ^{[1
]}

Kaga, H ^{[1
]}

机构：

[1] Hokkaido Natl Ind Res Inst, Sapporo, Hokkaido 0628517, Japan

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 13期

关键词：

D O I：

10.1016/S0957-4166(99)00260-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The efficient and direct resolution of cis-1-amino-2-indanol using Candida antarctica lipase B catalyzing the alcoholysis of its N,O-diacetyl derivative is reported. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2501 / 2503

页数：3

共 50 条

[41] Synthesis of enantiomerically pure trans-(1R,2R)- and cis-(1S,2R)-1-amino-2-indanol by lipase and ω-transaminase
Yun, H
Kim, J
Kinnera, K
Kim, BG
BIOTECHNOLOGY AND BIOENGINEERING, 2006, 93 (02) : 391 - 395
[42] cis-2-Amino-3,3-dimethyl-1-indanol: Synthesis, resolution and application as a highly efficient chiral auxiliary (vol 6, pg 2153, 1995)
Sudo, A
Saigo, K
TETRAHEDRON-ASYMMETRY, 1996, 7 (03) : 619 - 619
[43] Lipase-mediated partial resolution of 1,2-diol and 2-alkanol derivatives:: towards chiral building-blocks for pheromone synthesis
Izquierdo, I
Plaza, MT
Rodríguez, M
Tamayo, J
TETRAHEDRON-ASYMMETRY, 2000, 11 (08) : 1749 - 1756
[44] An efficient procedure for the resolution of α-cyano-α-fluoro-p-tolylacetic acid (CFTA) via the diastereomeric N-carbobenzyloxy-cis-1-amino-2-indanol esters
Fujiwara, T
Sasaki, M
Omata, K
Kabuto, C
Kabuto, K
Takeuchi, Y
TETRAHEDRON-ASYMMETRY, 2004, 15 (03) : 555 - 563
[45] A facile synthesis of (2R,3S)-1-amino-3-tert-butoxycarbonylamino-2-hydroxy-4-phenylbutane;: A useful component block of HIV protease inhibitor
Yuasa, Y
Yuasa, Y
Tsuruta, H
SYNTHETIC COMMUNICATIONS, 1998, 28 (03) : 395 - 401
[46] Practical synthesis of (2S,3S)-3-amino-2-hydroxy-4-phenylbutyric acid, a key component of HIV protease inhibitors
Shibata, N
Itoh, E
Terashima, S
CHEMICAL & PHARMACEUTICAL BULLETIN, 1998, 46 (04) : 733 - 735
[47] Research and Development of an Efficient Synthesis of hexahydrofuro[2,3-b]furan-3-ol moiety - A Key Component of the HIV protease inhibitor candidates
Yu, Richard H.
Polniaszek, Richard P.
Becker, Mark W.
Cook, Charles M.
Yu, Lok Him L.
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2007, 11 (06) : 972 - 980
[48] A Facile Synthesis of (2R,3S)-1-Amino-3-tert-butoxycarbonylamino-2- hydroxy-4-phenylbutane; A Useful Component Block of HIV Protease Inhibitor
Yuasa, Y.
Yuasa, Y.
Tsuruta, H.
Synthetic Communications, 28 (03):
[49] A stereospecific synthesis of both enantiomers of 2-(1'-amino-2'-methylpropyl) imidazole, a key synthon in the synthesis of SB 203386; A potent protease inhibitor
Pridgen, LN
Mokhallalati, MK
McGuire, MA
TETRAHEDRON LETTERS, 1997, 38 (08) : 1275 - 1278
[50] Highly stereocontrolled access to 1,1,1-trifluoro-2,3-epoxypropane via lipase-mediated kinetic resolution of 1,1,1-trifluoro-3-(phenylthio)propan-2-ol and its application
Shimizu, M
Sugiyama, K
Fujisawa, T
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1996, 69 (09) : 2655 - 2659

← 1 2 3 4 5 →