A Monte-Carlo based model of the AX-PET demonstrator and its experimental validation

被引：5

作者：

Solevi, P. ^{[1
]}

Oliver, J. F. ^{[1
]}

Gillam, J. E. ^{[1
]}

Bolle, E. ^{[2
]}

Casella, C. ^{[3
]}

Chesi, E. ^{[4
]}

De Leo, R. ^{[5
]}

Dissertori, G. ^{[3
]}

Fanti, V. ^{[6
,7
]}

Heller, M. ^{[8
]}

Lai, M. ^{[8
]}

Lustermann, W. ^{[3
]}

Nappi, E. ^{[5
]}

Pauss, F. ^{[3
]}

Rudge, A. ^{[4
]}

Ruotsalainen, U. ^{[9
]}

Schinzel, D. ^{[3
]}

Schneider, T. ^{[8
]}

Seguinot, J. ^{[8
]}

Stapnes, S. ^{[2
]}

Weilhammer, P. ^{[4
]}

Tuna, U. ^{[9
]}

Joram, C. ^{[8
]}

Rafecas, M. ^{[1
]}

机构：

[1] Univ Valencia, CSIC, IFIC, E-46071 Valencia, Spain

[2] Univ Oslo, Dept Phys, NO-0317 Oslo, Norway

[3] ETH, CH-8092 Zurich, Switzerland

[4] Ohio State Univ, Dept Phys, Columbus, OH 43210 USA

[5] Ist Nazl Fis Nucl, Sez Bari, I-70122 Bari, Italy

[6] Univ Cagliari, Cagliari, Italy

[7] Sezione Ist Nazl Fis Nucl, Cagliari, Italy

[8] CERN, PH Dept, CH-1211 Geneva, Switzerland

[9] Tampere Univ Technol, Dept Signal Proc, FI-33100 Tampere, Finland

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 2013年 / 58卷 / 16期

关键词：

SIMULATION TOOLKIT; GATE; SPECT; RECONSTRUCTION; MATRIX;

D O I：

10.1088/0031-9155/58/16/5495

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

AX-PET is a novel PET detector based on axially oriented crystals and orthogonal wavelength shifter (WLS) strips, both individually read out by silicon photo-multipliers. Its design decouples sensitivity and spatial resolution, by reducing the parallax error due to the layered arrangement of the crystals. Additionally the granularity of AX-PET enhances the capability to track photons within the detector yielding a large fraction of inter-crystal scatter events. These events, if properly processed, can be included in the reconstruction stage further increasing the sensitivity. Its unique features require dedicated Monte-Carlo simulations, enabling the development of the device, interpreting data and allowing the development of reconstruction codes. At the same time the non-conventional design of AX-PET poses several challenges to the simulation and modeling tasks, mostly related to the light transport and distribution within the crystals and WLS strips, as well as the electronics readout. In this work we present a hybrid simulation tool based on an analytical model and a Monte-Carlo based description of the AX-PET demonstrator. It was extensively validated against experimental data, providing excellent agreement.

引用

页码：5495 / 5510

页数：16

共 50 条

[1] Performance of the AX-PET Demonstrator
Beltrame, P.
Bolle, E.
Braem, A.
Casella, C.
Chesi, E.
Clinthorne, N.
De Leo, R.
Dissertori, G.
Djambazov, L.
Fanti, V.
Joram, C.
Kagan, H.
Lustermann, W.
Meddi, F.
Nappi, E.
Nessi-Tedaldi, F.
Oliver, J. F.
Pauss, F.
Rafecas, M.
Renker, D.
Rudge, A.
Ruotsalainen, U.
Schinzel, D.
Schneider, T.
Seguinot, J.
Solevi, P.
Stapnes, S.
Tuna, U.
Weilhammer, P.
NUCLEAR PHYSICS B-PROCEEDINGS SUPPLEMENTS, 2011, 215 : 34 - 36
[2] First Results from the AX-PET Demonstrator
Beltrame, P.
Bolle, E.
Braem, A.
Casella, C.
Chesi, E.
Clinthorne, N.
De Leo, R.
Dissertori, G.
Djambazov, L.
Fanti, V.
Joram, C.
Kagan, H.
Lustermann, W.
Meddi, F.
Nappi, E.
Nessi-Tedaldi, F.
Oliver, J. F.
Pauss, F.
Rafecas, M.
Renker, D.
Rudge, A.
Schinzel, D.
Schneider, T.
Seguinot, J.
Solevi, P.
Stapnes, S.
Weilhammer, P.
2009 IEEE NUCLEAR SCIENCE SYMPOSIUM CONFERENCE RECORD, VOLS 1-5, 2009, : 3096 - +
[3] Experimental validation of a PET Monte-Carlo simulator
Le Meunier, L
Mathy, F
Fagret, D
2004 IEEE NUCLEAR SCIENCE SYMPOSIUM CONFERENCE RECORD, VOLS 1-7, 2004, : 3343 - 3346
[4] The AX-PET demonstrator-Design, construction and characterization
Beltrame, P.
Bolle, E.
Braem, A.
Casella, C.
Chesi, E.
Clinthorne, N.
De Leo, R.
Dissertori, G.
Djambazov, L.
Fanti, V.
Heller, M.
Joram, C.
Kagan, H.
Lustermann, W.
Meddi, F.
Nappi, E.
Nessi-Tedaldi, F.
Oliver, J. F.
Pauss, F.
Rafecas, M.
Renker, D.
Rudge, A.
Schinzel, D.
Schneider, T.
Seguinot, J.
Solevi, P.
Stapnes, S.
Weilhammer, P.
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2011, 654 (01): : 546 - 559
[5] Long axial crystals for PET applications: the AX-PET demonstrator and beyond
Bolle, E.
Casella, C.
Chesi, E.
De Leo, R.
Dissertori, G.
Fanti, V.
Gillam, J. E.
Heller, M.
Holme, O.
Joram, C.
Lustermann, W.
Nappi, E.
Oliver, J. F.
Pauss, F.
Rafecas, M.
Ruotsalainen, U.
Schinzel, D.
Schneider, T.
Seguinot, J.
Solevi, P.
Stapnes, S.
Tuna, U.
Weilhammer, P.
2013 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE (NSS/MIC), 2013,
[6] The AX-PET experiment: A demonstrator for an axial Positron Emission Tomograph
Bolle, E.
Casella, C.
Chesi, E.
De Leo, R.
Dissertori, G.
Fanti, V.
Gillam, J. E.
Heller, M.
Joram, C.
Lustermann, W.
Nappi, E.
Oliver, J. F.
Pauss, F.
Rafecas, M.
Rudge, A.
Ruotsalainen, U.
Schinzel, D.
Schneider, T.
Seguinot, J.
Solevi, P.
Stapnes, S.
Tuna, U.
Weilhammer, P.
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2013, 718 : 126 - 129
[7] AX-PET, A DEMONSTRATOR FOR PET IMAGING USING LONG AXIALLY ORIENTED SCINTILLATING CRYSTALS
Beltrame, Paolo
Braem, Andre
Fanti, Viviana
Joram, Christian
Schneider, Thomas
Seguinot, Jacques
Casella, Chiara
Dissertori, Guenther
Djambazov, Lubomir
Lustermann, Werner
Nessi-Tedaldi, Francesca
Pauss, Felicitas
Schinzel, Dietrich
Solevi, Paola
Oliver, Josep F.
Rafecas, Magdalena
de Leo, Raffaele
Nappi, Eugenio
Chesi, Enrico
Cochran, Eric
Honscheid, Klaus
Kagan, Harris
Rudge, Alan
Smith, Shane
Weilhammer, Peter
Johnson, Ian
Renker, Dieter
Clinthorne, Neal
Huh, Sam
Bolle, Erlend
Stapnes, Steinar
Meddi, Franco
ASTROPARTICLE, PARTICLE AND SPACE PHYSICS, DETECTORS AND MEDICAL PHYSICS APPLICATIONS, 2010, 5 : 636 - 640
[8] AX-PET: from Demonstrator towards a Full-Ring Brain Scanner
Solevi, P.
ACTA PHYSICA POLONICA A, 2015, 127 (05) : 1462 - 1464
[9] Validation of a Monte-Carlo Markov Model for Schizophrenia
Dragomir, Alice
Angers, Jean-Francois
Tarride, Jean-Eric
Joober, Ridha
Perreault, Sylvie
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2010, 19 : S153 - S154
[10] PET SIMULATOR BASED ON MONTE-CARLO METHOD
PANI, R
PELLEGRINI, R
RUBIO, M
BANCI, M
SCOPINARO, F
EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1992, 19 (08): : 633 - 633

← 1 2 3 4 5 →