Synthesis of pyrimido[5'',4'':5',6']pyrido[2',3':4,5]-thieno[2,3-c]pyridazine and pyridazino[4',3':4,5]-thieno[3,2-b][1,8]naphthyridine, new tetraheterocyclic ring systems

被引：0

作者：

Quintela, JM

Veiga, MC

Peinador, C

Gonzalez, L

机构：

来源：

HETEROCYCLES | 1997年 / 45卷 / 09期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Preparation of a number of pyrimido[5 '',4 '':5',6']pyrido-[2',3':4,5]thieno[2,3-c]pyridazine derivatives (4a-h) has been effected by reaction of appropriately heterocyclic aminonitrile precursor (1) and N,N-dimethyldichloromethyleniminium chloride. In addition, pyridazino[4',3':4,5]thieno[3,2-b][1,8]naphthyridines (9a-i), were prepared via the Friedlander synthesis of the N-heteroaromatic carbaldehyde (8) with acyclic, cyclic, heterocyclic or alpha,beta-unsaturated ketones and other active methylene compounds.

引用

页码：1733 / 1743

页数：11

共 50 条

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