Synthesis of pyrimido[5'',4'':5',6']pyrido[2',3':4,5]-thieno[2,3-c]pyridazine and pyridazino[4',3':4,5]-thieno[3,2-b][1,8]naphthyridine, new tetraheterocyclic ring systems

被引：0

作者：

Quintela, JM

Veiga, MC

Peinador, C

Gonzalez, L

机构：

来源：

HETEROCYCLES | 1997年 / 45卷 / 09期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Preparation of a number of pyrimido[5 '',4 '':5',6']pyrido-[2',3':4,5]thieno[2,3-c]pyridazine derivatives (4a-h) has been effected by reaction of appropriately heterocyclic aminonitrile precursor (1) and N,N-dimethyldichloromethyleniminium chloride. In addition, pyridazino[4',3':4,5]thieno[3,2-b][1,8]naphthyridines (9a-i), were prepared via the Friedlander synthesis of the N-heteroaromatic carbaldehyde (8) with acyclic, cyclic, heterocyclic or alpha,beta-unsaturated ketones and other active methylene compounds.

引用

页码：1733 / 1743

页数：11

共 50 条

[31] Synthesis of new pyrido[4",3":4′,5′]thieno[2′,3′:4,5]pyrimido-[2,1-B][1,3,4]thiadiazine derivatives
Ahmed, EK
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2002, 177 (04) : 989 - 1000
[32] Synthesis of Some Novel Thieno[2,3-c]pyridazines, Pyrimidothienopyridazines and Related Triazolo[1"5":1′,6′]pyrimido[4′,5′:4,5]thieno [2,3-c]pyridazines
El-Dean, A. M. Kamal
Al-Kamali, A. S. N.
AFINIDAD, 2009, 66 (539) : 70 - 75
[33] Synthesis of Isomeric Isothiazolo[4′,3′:4,5]- and Isothiazolo[4′,5′:4,5]thieno[3,2-b]pyrano[2,3-d]pyridines by Combination of Domino Reactions
Shestopalov, Anatoliy M.
Larionova, Natalia A.
Fedorov, Alexander E.
Rodinovskaya, Lyudmila A.
Mortikov, Valery Yu.
Zubarev, Andrey A.
Bushmarinov, Ivan S.
ACS COMBINATORIAL SCIENCE, 2013, 15 (10) : 541 - 545
[34] Synthesis and antitumor activity of pyrano[4′,3′:4,5]pyrido[2, 3-b]thieno[3,2-d]-1,2,3-triazine and l,2,3-triazino[4′,5′:4, 5|thieno-[2,3-c]isoquinoline derivatives
Paronikyan E.G.
Noravyan A.S.
Akopyan Sh.F.
Arsenyan F.G.
Stepanyan G.M.
Garibdzhanyan B.T.
Pharmaceutical Chemistry Journal, 2006, 40 (6) : 293 - 295
[35] Reactions with pyridinethione derivatives:: Synthesis and characterization of thienyl[2,3-b]pyridine, pyrido[2′,3′:4,5] thieno[2,3-b]pyridazine, pyrido[2′,3′:4,5] thieno[2,3-b]-pyrimidinone, pyrazolino[3′,4′:4,5] thieno[2,3-b]pyridine and aminopyrazolo[3,4-b]pyridine derivatives
Attaby, FA
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1997, 126 : 27 - 38
[36] SYNTHESIS OF PYRIMIDO[4',5'-4,5]THIENO[2,3-B]QUINOLIN-4(3H)-ONES
RAJ, TT
AMBEKAR, SY
JOURNAL OF CHEMICAL RESEARCH-S, 1988, (02): : 50 - 50
[37] Synthesis and biological activity of some novel thieno[2,3-b]quinoline, quinolino[3',2':4,5] thieno[3,2-d]pyrimidine and pyrido[2',3':4,5] thieno[2,3-b]quinoline derivatives
El-Gaby, MSA
Abdel-Gawad, SM
Ghorab, MM
Heiba, HI
Aly, HM
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2006, 181 (02) : 279 - 297
[38] New Cyclopenta[4′,5′] pyrido[3′,2′:4,5]thieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidines and Cyclopenta[4′,5′]pyrido[3′,2′:4,5]thieno[2,3-e][1,2,4]triazolo[1,5-c]pyrimidines: Synthesis and Antimicrobial Activities
Sirakanyan, Samvel N.
Spinelli, Domenico
Geronikaki, Athina
Kartsev, Viktor G.
Hakobyan, Elmira K.
Panosyan, Henrik A.
Stepanyan, Hrachya M.
Zuppiroli, Luca
Hovakimyan, Anush A.
CURRENT ORGANIC CHEMISTRY, 2017, 21 (13) : 1227 - 1241
[39] Synthesis and characterization of new quinazolinylmethylsulfanylpyridines, quinazolinylthieno[2,3-b]pyridines and pyrido[3",2":4′,5′] thieno[3′,2′:4,5]pyrimido[6,1-b]quinazolines
El-Ossaily, Yasser A.
Al-Taifi, Elham A.
Bakhite, Etify A.
Marae, Islam S.
Zaki, Remon M.
ARKIVOC, 2019, : 446 - 458
[40] SYNTHESIS OF SOME NEW PYRIMIDO[4',5'-4,5]THIENO[2,3-B]QUINOLINE DERIVATIVES
BAKHITE, EA
ABBADY, MS
RADWAN, SM
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1993, 58 (06) : 1457 - 1462

← 1 2 3 4 5 →