Synthesis of pyrimido[5'',4'':5',6']pyrido[2',3':4,5]-thieno[2,3-c]pyridazine and pyridazino[4',3':4,5]-thieno[3,2-b][1,8]naphthyridine, new tetraheterocyclic ring systems

被引：0
|
作者：
Quintela, JM
Veiga, MC
Peinador, C
Gonzalez, L
机构：
来源：
HETEROCYCLES | 1997年 / 45卷 / 09期
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D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Preparation of a number of pyrimido[5 '',4 '':5',6']pyrido-[2',3':4,5]thieno[2,3-c]pyridazine derivatives (4a-h) has been effected by reaction of appropriately heterocyclic aminonitrile precursor (1) and N,N-dimethyldichloromethyleniminium chloride. In addition, pyridazino[4',3':4,5]thieno[3,2-b][1,8]naphthyridines (9a-i), were prepared via the Friedlander synthesis of the N-heteroaromatic carbaldehyde (8) with acyclic, cyclic, heterocyclic or alpha,beta-unsaturated ketones and other active methylene compounds.
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页码：1733 / 1743
页数：11
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