A synthesis of new pyrido[2',3':4,5]thieno[2,3-c]pyridazine derivatives

被引：0

作者：

Veiga, MC

Quintela, JM

Peinador, C

机构：

来源：

HETEROCYCLES | 1996年 / 43卷 / 05期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5-Amino-3,4-diphenylthieno[2,3-c]pyridazine-6-carbaldehyde is formed by DIBAL reduction from the corresponding cyano precursor 5-amino-3,4-diphenylthieno[2,3-c]pyridazine-6-carbonitrile (1). A variety of substituted pyrido[2',3':4,5]thieno[2,3-c]pyridazines were synthesized from 5-amino-3,4-diphenylthieno[2,3-c]pyridazine-6-carbaldehyde (2) by Friedlander condensation with acyclic, cyclic, heterocyclic or alpha,beta-unsatured ketones and other active methylene compounds.

引用

页码：1073 / 1081

页数：9

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