Scalarane-based metabolites isolated from the antimitotic extract of the marine sponge Hyrtios erectus

被引:6
|
作者
Diaz-Marrero, Ana R. [1 ]
Matainaho, Teatulohi [2 ]
van Soest, Rob [3 ]
Roberge, Michel [4 ]
Andersen, Raymond J. [1 ]
机构
[1] Univ British Columbia, Dept Chem & Earth & Ocean Sci, Vancouver, BC, Canada
[2] Univ Papua New Guinea, Sch Med & Hlth Sci, Discipline Pharmacol, Ncd, Papua N Guinea
[3] Univ Amsterdam, Zool Museum, Amsterdam, Netherlands
[4] Univ British Columbia, Dept Biochem & Mol Biol, Vancouver, BC, Canada
关键词
cell-based assay; cytotoxicity; seterterpenoids; scalarane framework;
D O I
10.1080/14786410701824023
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Two novel sesterterpenes, 1 and 3, containing a scalarane-based framework, have been isolated from the sponge Hyrtios erectus collected in Papua New Guinea. Their structures and relative stereochemistry have been elucidated by analysis of their spectroscopic data.
引用
收藏
页码:1304 / 1309
页数:6
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