Biologically Responsive Polymeric Nanoparticles for Drug Delivery

被引：175
|
作者：
Colson, Yolonda L. [1 ]
Grinstaff, Mark W. [2 ,3 ]
机构：
[1] Brigham & Womens Hosp, Dept Surg, Div Thorac Surg, Boston, MA 02215 USA
[2] Boston Univ, Dept Biomed Engn, Boston, MA 02215 USA
[3] Boston Univ, Dept Chem, Boston, MA 02215 USA
来源：
ADVANCED MATERIALS | 2012年 / 24卷 / 28期
基金：
美国国家科学基金会;
关键词：
responsive system; triggered drug delivery; nanoparticles; pH; oxidation; POLY(BETA-AMINO ESTER) NANOPARTICLES; TUMOR-TARGETED DELIVERY; PH-SENSITIVE SYSTEM; LOADED EXPANSILE NANOPARTICLES; IN-VIVO; HYDROPHOBIC DRUGS; LYMPH-NODES; PACLITAXEL; PARTICLES; DEGRADATION;
D O I：
10.1002/adma.201200420
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Responsive nanoparticles that release their drug cargo in accordance with a change in pH or oxidative stress are of significant clinical interest as this approach offers the opportunity to link drug delivery to a specific location or disease state. This research news article reviews the current state of this field by examining a series of published articles that highlight the novelty and benefits of using responsive polymeric particles to achieve functionally-targeted drug delivery.
引用
收藏
页码：3878 / 3886
页数：9
相关论文
共 50 条
  • [1] Responsive polymeric nanoparticles for controlled drug delivery
    Neumann, Kevin
    Lilienkampf, Annamaria
    Bradley, Mark
    [J]. POLYMER INTERNATIONAL, 2017, 66 (12) : 1756 - 1764
  • [2] Stimuli responsive polymeric nanoparticles in regulated drug delivery for cancer
    Yadav, Deepak
    Suri, Suruchi
    Chaudhary, Anis A.
    Hemant
    Beg, Mohd N.
    Garg, Veena
    Asif, Mohd
    Ahmad, Altaf
    [J]. POLISH JOURNAL OF CHEMICAL TECHNOLOGY, 2012, 14 (01) : 57 - 64
  • [3] Polymeric nanoparticles responsive to intracellular ROS for anticancer drug delivery
    Xu, Long
    Zhao, Mingying
    Gao, Wenxia
    Yang, Yidi
    Zhang, Jianfeng
    Pu, Yuji
    He, Bin
    [J]. COLLOIDS AND SURFACES B-BIOINTERFACES, 2019, 181 : 252 - 260
  • [4] Polymeric Nanoparticles for Drug Delivery
    Beach, Maximilian A.
    Nayanathara, Umeka
    Gao, Yanting
    Zhang, Changhe
    Xiong, Yijun
    Wang, Yufu
    Such, Georgina K.
    [J]. CHEMICAL REVIEWS, 2024, 124 (09) : 5505 - 5616
  • [5] pH-responsive polymeric nanoparticles with tunable sizes for targeted drug delivery
    Kong, Mengle
    Peng, Xinwen
    Cui, Hao
    Liu, Peiwen
    Pang, Bo
    Zhang, Kai
    [J]. RSC ADVANCES, 2020, 10 (09) : 4860 - 4868
  • [6] Hypoxia-responsive polymeric nanoparticles for tumor-targeted drug delivery
    Thambi, Thavasyappan
    Deepagan, V. G.
    Yoon, Hong Yeol
    Han, Hwa Seung
    Kim, Seol-Hee
    Son, Soyoung
    Jo, Dong-Gyu
    Ahn, Cheol-Hee
    Suh, Yung Doug
    Kim, Kwangmeyung
    Kwon, Ick Chan
    Lee, Doo Sung
    Park, Jae Hyung
    [J]. BIOMATERIALS, 2014, 35 (05) : 1735 - 1743
  • [7] Environment-responsive Polymeric Nanoparticles as Drug Delivery Systems for Cancer Therapy
    Yang Yang
    She Wen-Chuan
    Luo Kui
    Gu Zhong-Wei
    [J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2013, 40 (10) : 1039 - 1048
  • [8] Hydrogen peroxide-responsive polymeric nanoparticles for diagnostics and drug delivery in inflammatory disease
    Lux, Caroline de Gracia
    Joshi-Barr, Shivanjali
    Mahmoud, Enas A.
    Almutairi, Adah
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
  • [9] Facile Fabrication of Oxidation-Responsive Polymeric Nanoparticles for Effective Anticancer Drug Delivery
    Huang, Yamei
    Chen, Qiubing
    Ma, Panpan
    Song, Heliang
    Ma, Xiaoqian
    Ma, Ya
    Zhou, Xin
    Gou, Shuangquan
    Xu, Zhigang
    Chen, Jiucun
    Xiao, Bo
    [J]. MOLECULAR PHARMACEUTICS, 2019, 16 (01) : 49 - 59
  • [10] Polymeric Nanoparticles for Retinal Drug Delivery
    Rad-Malekshahi, Mazda
    [J]. JOURNAL OF OPHTHALMIC & VISION RESEARCH, 2024, 19 (01) : 4 - 5
12345