Coupling reactions with haloaromatic amines and alcohols for a practical synthetic route to 2-substituted aminophenyl and hydroxyphenyl pyridines

被引：9
|
作者：
Kim, Seung-Hoi [1 ]
Rieke, Reuben D. [1 ]
机构：
[1] Rieke Met Inc, Lincoln, NE 68521 USA
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 50期
关键词：
DIRECT ARYLATION; CROSS-COUPLINGS; N-OXIDES; EFFICIENT; 2,2'-BIPYRIDINES; MAGNESIATION; CHLORIDE; YIELD;
D O I：
10.1016/j.tetlet.2009.09.160
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A practical synthetic route to 2-substituted aminophenyl and hydroxyphenyl pyridines has been developed. It has been accomplished by the cross-coupling reactions of readily available 2-pyridylzinc bromides with haloaromatic amines and alcohols under mild conditions. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：6985 / 6988
页数：4
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