Synthesis of 2-substituted furanonaphthoquinones using directed metalation and cross coupling reactions

被引：13
|
作者：
Starling, SM
Raslan, DS
de Oliveira, AB
机构：
[1] Univ Fed Minas Gerais, Fac Farm, BR-30180112 Belo Horizonte, MG, Brazil
[2] Univ Fed Minas Gerais, ICEx, Dept Quim, BR-30180112 Belo Horizonte, MG, Brazil
来源：
SYNTHETIC COMMUNICATIONS | 1998年 / 28卷 / 06期
关键词：
D O I：
10.1080/00397919808003070
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A synthetic method for the preparation of C-2 substituted furanonaphthoquinones from ortholithium-benzamide and the 2-furan-carboxaldehyde derivative is described. Four 2-alkyl-furanonaphthoquinones and the 2-phenyl-substituted were prepared via phathalide. This route has been shown to be general application to the synthesis of furanonaphthoquinones.
引用
收藏
页码：1013 / 1030
页数：18
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