Functional characterization of IGF-1R antibodies and possible implications for clinical safety and efficacy

被引：0
|
作者：
Kuenkele, Klaus-Peter [1 ]
Hofmann, Marco H. [1 ]
Scheiblich, Stefan [1 ]
Wartha, Katharina [1 ]
Klein, Christian [2 ]
机构：
[1] Roche Diagnost GmbH, Penzberg, Germany
[2] Roche Gylcart AG, Schlieren, Switzerland
来源：
CANCER RESEARCH | 2011年 / 71卷
关键词：
D O I：
10.1158/1538-7445.AM2011-LB-397
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
LB-397
引用
收藏
页数：2
相关论文
共 50 条
  • [31] A role for IGF-1R targeted therapy in SCLC?
    Gately, K.
    Collins, I.
    Forde, L.
    Al-Alao, A.
    O'Byrne, K. J.
    LUNG CANCER, 2010, 67 : S12 - S12
  • [32] Does Reduced IGF-1R Signaling in Igf1r+/- Mice Alter Aging?
    Bokov, Alex F.
    Garg, Neha
    Ikeno, Yuji
    Thakur, Sachin
    Musi, Nicolas
    DeFronzo, Ralph A.
    Zhang, Ning
    Erickson, Rebecca C.
    Gelfond, Jon
    Hubbard, Gene B.
    Adamo, Martin L.
    Richardson, Arlan
    PLOS ONE, 2011, 6 (11):
  • [33] Blockade of IGF-1R—not effective in neuroendocrine tumours
    Steven K. Libutti
    Nature Reviews Endocrinology, 2013, 9 : 389 - 390
  • [34] BMS-754807, a small molecule inhibitor of IGF-1R for clinical development
    Carboni, Joan
    Wittman, M.
    Yang, Z.
    Fairchild, C.
    Cantor, G.
    Lee, F.
    Finckenstein, F.
    Cheng, S.
    Chen, C.
    Discenza, L.
    Attar, R.
    Frennesson, D.
    Greer, A.
    Hurlburt, W.
    Li, A.
    Hillerman, S.
    Cao, C.
    Liu, P.
    Johnson, W.
    Mastalarz, H.
    Menard, K.
    Sang, X.
    Saulnier, M.
    Trainor, G.
    Velaparthi, U.
    Vyas, D.
    Zhang, G.
    Zimmerman, K.
    Kramer, R.
    Gottardis, M.
    CANCER RESEARCH, 2009, 69
  • [35] Revisiting the IGF-1R as a breast cancer target
    Roudy Chiminch Ekyalongo
    Douglas Yee
    npj Precision Oncology, 1
  • [36] Targeting the IGF-1R: the tale of the tortoise and the hare
    Crudden, Caitrin
    Girnita, Ada
    Girnita, Leonard
    FRONTIERS IN ENDOCRINOLOGY, 2015, 6
  • [37] Evaluation of IGF-1 and IGF-1R in Triple Negative Breast Cancer
    Desai, S.
    Vora, A.
    Kurani, H.
    Nair, N.
    Sable, M.
    Shet, T.
    Gupta, S.
    Parmar, V.
    Badwe, R.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2012, 14 (06): : 723 - 723
  • [38] Advances of IGF-1R inhibitors in Graves' ophthalmopathy
    Wang, Meilan
    Liu, Lian
    INTERNATIONAL OPHTHALMOLOGY, 2024, 44 (01)
  • [39] Insulin Receptor A and IGF-1R in AML - Letter
    Chapuis, Nicolas
    Lacombe, Catherine
    Tamburini, Jerome
    Bouscary, Didier
    Mayeux, Patrick
    CANCER RESEARCH, 2010, 70 (17) : 7010 - 7010
  • [40] Disorders of IGFs and IGF-1R signaling pathways
    Forbes, Briony E.
    Blyth, Andrew J.
    Wit, Jan M.
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2020, 518
12345