Functional characterization of IGF-1R antibodies and possible implications for clinical safety and efficacy

被引：0
|
作者：
Kuenkele, Klaus-Peter [1 ]
Hofmann, Marco H. [1 ]
Scheiblich, Stefan [1 ]
Wartha, Katharina [1 ]
Klein, Christian [2 ]
机构：
[1] Roche Diagnost GmbH, Penzberg, Germany
[2] Roche Gylcart AG, Schlieren, Switzerland
来源：
CANCER RESEARCH | 2011年 / 71卷
关键词：
D O I：
10.1158/1538-7445.AM2011-LB-397
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
LB-397
引用
收藏
页数：2
相关论文
共 50 条
  • [21] The Role of IGF-1R in Pediatric Malignancies
    Kim, Su Young
    Toretsky, Jeffrey A.
    Scher, Daniel
    Helman, Lee J.
    ONCOLOGIST, 2009, 14 (01): : 83 - 91
  • [22] Radiolabelled figitumumab for IGF-1R imaging
    Forbes, John
    Simms, Ryan
    Wu, T.
    Drewry, Joel
    Collens, Sean
    Kelly, Ryan
    Stephenson, Karin
    Burak, Eric
    McCarthy, Timothy
    Valliant, John
    JOURNAL OF NUCLEAR MEDICINE, 2014, 55
  • [23] Molecular Imaging of IGF-1R in Cancer
    Sun, Yingying
    Sun, Xilin
    Shen, Baozhong
    MOLECULAR IMAGING, 2017, 16
  • [24] IGF-1R targeted treatment of sarcoma
    Toretsky, Jeffrey A.
    Gorlick, Richard
    LANCET ONCOLOGY, 2010, 11 (02): : 105 - 106
  • [25] Blockade of IGF/IGF-1R signaling axis with soluble IGF-1R mutants suppresses the cell proliferation and tumor growth of human osteosarcoma
    Cao, Daigui
    Lei, Yan
    Ye, Zhenyu
    Zhao, Ling
    Wang, Hao
    Zhang, Jing
    He, Fang
    Huang, Linjuan
    Shi, Deyao
    Liu, Qing
    Ni, Na
    Pakvasa, Mikhail
    Wagstaff, William
    Zhao, Xia
    Fu, Kai
    Tucker, Andrew B.
    Chen, Connie
    Reid, Russell R.
    Haydon, Rex C.
    Luu, Hue H.
    He, Tong-Chuan
    Liao, Zhan
    AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 10 (10): : 3248 - +
  • [26] Expression and significance of IGF-1 and IGF-1R in thyroid nodules
    Liu, Ying-Jian
    Qiang, Wei
    Shi, Jing
    Lv, Si-Qing
    Ji, Mei-Ju
    Shi, Bing-Yin
    ENDOCRINE, 2013, 44 (01) : 158 - 164
  • [27] Expression and significance of IGF-1 and IGF-1R in thyroid nodules
    Ying-Jian Liu
    Wei Qiang
    Jing Shi
    Si-Qing Lv
    Mei-Ju Ji
    Bing-Yin Shi
    Endocrine, 2013, 44 : 158 - 164
  • [28] IGF及IGF-1R与大肠癌
    苏文利
    杨国樑
    熊斌
    辽宁医学杂志, 2000, (06) : 322 - 323
  • [29] Chronic Loop Diuretic Treatment Induces Tubular Remodeling via IGF-1R Dependent and IGF-1R Independent Signaling
    Krauson, Aram J.
    Walczak, Elisabeth M.
    Nizar, Jon M.
    Elsayed, Ragwa
    Iyer, Sonali M.
    Bhalla, Vivek
    CIRCULATION, 2017, 136
  • [30] IGF-1R and EGFR expression and IGF-1R mutational status in non-small cell lung cancer (NSCLC)
    Forde, Lydia
    Gately, Kathy
    Gray, Stephen
    Cuffe, Sinead
    Easty, David
    O'Byrne, Ken
    CANCER RESEARCH, 2010, 70
12345