An effective synthesis of β-aryl substituted isotetronic acids via Suzuki coupling

被引：5

作者：

Chen, Huan Sheng ^{[1
]}

Ma, Xia Ping ^{[1
]}

Li, Zhi Ming ^{[1
]}

Wang, Quan Rui ^{[1
]}

Tao, Feng Gang ^{[1
]}

机构：

[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2008年 / 19卷 / 11期

关键词：

Isotetronic acids; Palladium; Suzuki coupling; Arylboronic acids;

D O I：

10.1016/j.cclet.2008.09.016

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Isotetronic acids are of great agricultural and pharmacological relevance and occur in a number of natural products. A convenient synthetic pathway to beta-aryl substituted isotetronic acid derivatives was developed via Suzuki cross-coupling of the corresponding beta-bromo substituted isotetronic acid derivatives with arylboronic acids under palladium acetate catalysis. Good to excellent yields have been achieved. (C) 2008 Quan Rui Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

引用

页码：1309 / 1311

页数：3

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