From combined therapy to fixed-dose combinations

被引:0
|
作者
Kolos, I. P. [1 ]
Boytsov, S. A. [1 ]
机构
[1] Fed Agcy High Med Technol, Moscow, Russia
来源
关键词
Fixed-dose combination; arterial hypertension; trandolapril; verapamil;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Due to low effectiveness of arterial hypertension (AH) monotherapy, recent debates have concentrated on evidence-based effectiveness and safety of combined AH therapy. To improve treatment compliance, reduce treatment costs, and increase therapy effectiveness, fixed-dose combined anti hypertensive therapy is used more and more actively. One of such fixed-dose combinations, with proved effectiveness and safety, is Tarka medication, including trandolapril and verapamil. The article reviews the literature data demonstrating fixed-dose trandolapril+verapamil combination effects on blood pressure level and target organ damage in AH, renal failure, diabetes mellitus, and coronary heart disease.
引用
收藏
页码:89 / 94
页数:6
相关论文
共 50 条
  • [41] Combined antihypertensive therapy focus on a fixed-dose combination of an ACE inhibitor and a diuretic
    Astakhova, Z. T.
    Kanukova, F. U.
    Rappoport, A., V
    Tautieva, I. Zh
    Kuova, Zh A.
    Dzukaeva, Z. Z.
    Aydarova, V. A.
    [J]. RUSSIAN JOURNAL OF CARDIOLOGY, 2010, (05): : 68 - 72
  • [42] Fixed-dose combinations for treatment of diabetes unsafe, finds study
    Nischal, P. M.
    [J]. NATIONAL MEDICAL JOURNAL OF INDIA, 2018, 31 (03): : 191 - 191
  • [43] An overview of fixed-dose combinations of antihypertensive drugs in South Africa
    Schellacka, Natalie
    Malana, Lucille
    [J]. SOUTH AFRICAN FAMILY PRACTICE, 2014, 56 (04) : 206 - 211
  • [45] The role of fixed-dose combinations in the treatment of hypertension - expert opinion
    Gaciong, Zbigniew
    Narkiewicz, Krzysztof
    Tykarski, Andrzej
    Filipiak, Krzysztof J.
    Opolski, Grzegorz
    [J]. ARTERIAL HYPERTENSION, 2009, 13 (06): : 363 - 370
  • [46] FIXED-DOSE COMBINATIONS IN HIGH BLOOD PRESSURE: COMBINE AIIA
    Schnitzer, Wolfgang
    [J]. JOURNAL FUR HYPERTONIE, 2005, 9 (04): : 22 - 22
  • [47] Evaluation of the registration status of fixed-dose drug combinations in Nepal
    Poudel, Arjun
    Ibrahim, Mohamed Izham B. Mohamed
    Mishra, Pranaya
    Palaian, Subish
    [J]. JOURNAL OF PHARMACEUTICAL HEALTH SERVICES RESEARCH, 2018, 9 (01) : 41 - 46
  • [48] Irrational ophthalmic fixed-dose combinations for dry eye syndrome
    Kshirsagar, Nilima A.
    Munshi, Renuka
    Bavdekar, Sandeep B.
    Saxena, Rohit
    [J]. INDIAN JOURNAL OF OPHTHALMOLOGY, 2022, 70 (10) : 3687 - 3689
  • [49] Fixed-Dose Combinations of Pioglitazone and Metformin for Lung Cancer Prevention
    Seabloom, Donna E.
    Galbraith, Arthur R.
    Haynes, Anna M.
    Antonides, Jennifer D.
    Wuertz, Beverly R.
    Miller, Wendy A.
    Miller, Kimberly A.
    Steele, Vernon E.
    Miller, Mark Steven
    Clapper, Margie L.
    O'Sullivan, M. Gerard
    Ondrey, Frank G.
    [J]. CANCER PREVENTION RESEARCH, 2017, 10 (02) : 116 - 123
  • [50] Enhanced antitumor activity of fixed-dose combinations of celecoxib and antihypertensives
    Lee, C.
    Hwang, L.
    D'Cruz, O.
    Ng, K.
    Trieu, V.
    [J]. ANNALS OF ONCOLOGY, 2017, 28