From combined therapy to fixed-dose combinations

被引:0
|
作者
Kolos, I. P. [1 ]
Boytsov, S. A. [1 ]
机构
[1] Fed Agcy High Med Technol, Moscow, Russia
来源
关键词
Fixed-dose combination; arterial hypertension; trandolapril; verapamil;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Due to low effectiveness of arterial hypertension (AH) monotherapy, recent debates have concentrated on evidence-based effectiveness and safety of combined AH therapy. To improve treatment compliance, reduce treatment costs, and increase therapy effectiveness, fixed-dose combined anti hypertensive therapy is used more and more actively. One of such fixed-dose combinations, with proved effectiveness and safety, is Tarka medication, including trandolapril and verapamil. The article reviews the literature data demonstrating fixed-dose trandolapril+verapamil combination effects on blood pressure level and target organ damage in AH, renal failure, diabetes mellitus, and coronary heart disease.
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页码:89 / 94
页数:6
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