From combined therapy to fixed-dose combinations

被引：0
|
作者：
Kolos, I. P. [1 ]
Boytsov, S. A. [1 ]
机构：
[1] Fed Agcy High Med Technol, Moscow, Russia
来源：
CARDIOVASCULAR THERAPY AND PREVENTION | 2008年 / 7卷 / 04期
关键词：
Fixed-dose combination; arterial hypertension; trandolapril; verapamil;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Due to low effectiveness of arterial hypertension (AH) monotherapy, recent debates have concentrated on evidence-based effectiveness and safety of combined AH therapy. To improve treatment compliance, reduce treatment costs, and increase therapy effectiveness, fixed-dose combined anti hypertensive therapy is used more and more actively. One of such fixed-dose combinations, with proved effectiveness and safety, is Tarka medication, including trandolapril and verapamil. The article reviews the literature data demonstrating fixed-dose trandolapril+verapamil combination effects on blood pressure level and target organ damage in AH, renal failure, diabetes mellitus, and coronary heart disease.
引用
收藏
页码：89 / 94
页数：6
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