Electrokinetic Biomolecule Preconcentration Using Xurography-Based Micro-Nano-Micro Fluidic Devices

被引：28
|
作者：
Yuan, Xichen [1 ]
Renaud, Louis [1 ]
Audry, Marie-Charlotte [1 ]
Kleimann, Pascal [1 ]
机构：
[1] Univ Lyon 1, CNRS, INL UMR5270, F-69622 Villeurbanne, France
来源：
ANALYTICAL CHEMISTRY | 2015年 / 87卷 / 17期
关键词：
CONCENTRATION POLARIZATION; NANOPOROUS MEMBRANES; TRANSPORT PHENOMENA; SAMPLE STACKING; ELECTROPHORESIS; PROPAGATION; SEPARATION; PROTEINS; ASSAY;
D O I：
10.1021/acs.analchem.5b01352
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
In this paper we introduce a low cost rapid prototyping framework for designing Micro-Nano-Micro (MNM) fluidic preconcentration device based on ion concentration polarization (ICP) phenomenon. Xurography-based microchannels are separated by a strip of ion perm-selective Nafion membrane which plays the role of nanofluidic potential barrier for the negatively charged molecules. As a result, by using this rapid and inexpensive fabrication technique, it is possible to get preconcentration plugs as high as 5000 fold with an original symmetric electroosmotic flow (EOF) condition. Due to its simplicity and performance, this device could be implemented in various bioanalysis systems.
引用
收藏
页码：8695 / 8701
页数：7
相关论文
共 50 条
  • [41] Editorial for the Special Issue on Wide Bandgap Semiconductor Based Micro/Nano Devices
    Seo, Jung-Hun
    MICROMACHINES, 2019, 10 (03)
  • [42] Optically Induced Dielectrophoresis Based Automatic Assembly of Micro/Nano-Devices
    Zheng, M. J.
    Qu, Y. L.
    Zhang, Y. Z.
    Dong, Z. L.
    INTEGRATED FERROELECTRICS, 2013, 145 (01) : 24 - 31
  • [43] Molecular motors-based micro- and nano-biocomputation devices
    Nicolau, Dan V.
    Nicolau, Dan V., Jr.
    Solana, Gerardin
    Hanson, Kristi L.
    Filipponi, Luisa
    Wang, Lisen
    Lee, Abraham P.
    MICROELECTRONIC ENGINEERING, 2006, 83 (4-9) : 1582 - 1588
  • [44] Quality Control of Ethanol-Based Hand Sanitizer Gels in Micro-Opto-Fluidic Devices
    Bello, Valentina
    Bodo, Elisabetta
    Merlo, Sabina
    2021 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO), 2021,
  • [45] Experimental analysis and numerical simulation of sintered micro-fluidic devices using powder hot embossing process
    Sahli, M. (sahlisofiane2@yahoo.fr), 1600, Springer London (99): : 5 - 8
  • [46] Using nonlinear dynamics for performance enhancement in resonant micro and nano-scale devices
    Turner, KL
    Baskaran, R
    Zhang, WH
    42ND IEEE CONFERENCE ON DECISION AND CONTROL, VOLS 1-6, PROCEEDINGS, 2003, : 2650 - 2651
  • [47] Characterisation and replication of metallic micro-fluidic devices using three different powders processed by hot embossing
    Sahli, M.
    Gelin, J. -C.
    Barriere, T.
    POWDER TECHNOLOGY, 2013, 246 : 284 - 302
  • [48] Experimental analysis and numerical simulation of sintered micro-fluidic devices using powder hot embossing process
    Sahli, M.
    Mamen, B.
    Ou, H.
    Gelin, J. -C.
    Barriere, T.
    Assoul, M.
    INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY, 2018, 99 (5-8): : 1141 - 1154
  • [49] Strategies on improving the micro-fluidic devices using the nonlinear electro- and thermo-kinetic phenomena
    Sugioka, Hideyuki
    ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2015, 226 : 44 - 53
  • [50] Experimental analysis and numerical simulation of sintered micro-fluidic devices using powder hot embossing process
    M. Sahli
    B. Mamen
    H. Ou
    J.-C. Gelin
    T. Barrière
    M. Assoul
    The International Journal of Advanced Manufacturing Technology, 2018, 99 : 1141 - 1154
12345