Electrokinetic Biomolecule Preconcentration Using Xurography-Based Micro-Nano-Micro Fluidic Devices

被引：28

作者：

Yuan, Xichen ^{[1
]}

Renaud, Louis ^{[1
]}

Audry, Marie-Charlotte ^{[1
]}

Kleimann, Pascal ^{[1
]}

机构：

[1] Univ Lyon 1, CNRS, INL UMR5270, F-69622 Villeurbanne, France

来源：

ANALYTICAL CHEMISTRY | 2015年 / 87卷 / 17期

关键词：

CONCENTRATION POLARIZATION; NANOPOROUS MEMBRANES; TRANSPORT PHENOMENA; SAMPLE STACKING; ELECTROPHORESIS; PROPAGATION; SEPARATION; PROTEINS; ASSAY;

D O I：

10.1021/acs.analchem.5b01352

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In this paper we introduce a low cost rapid prototyping framework for designing Micro-Nano-Micro (MNM) fluidic preconcentration device based on ion concentration polarization (ICP) phenomenon. Xurography-based microchannels are separated by a strip of ion perm-selective Nafion membrane which plays the role of nanofluidic potential barrier for the negatively charged molecules. As a result, by using this rapid and inexpensive fabrication technique, it is possible to get preconcentration plugs as high as 5000 fold with an original symmetric electroosmotic flow (EOF) condition. Due to its simplicity and performance, this device could be implemented in various bioanalysis systems.

引用

页码：8695 / 8701

页数：7

共 50 条

[31] Active cooling of integrated circuits and optoelectronic devices using a micro configured thermoelectric and fluidic system
Yu, EC
Wang, DM
Kim, S
Przekwas, A
ITHERM 2000: SEVENTH INTERSOCIETY CONFERENCE ON THERMAL AND THERMOMECHANICAL PHENOMENA IN ELECTRONIC SYSTEMS, VOL 2, PROCEEDINGS, 2000, : 134 - 139
[32] Biodetection using micro-physiometry tools based on electrokinetic phenomena
Pethig, R
DEFENSE AGAINST BIOTERROR: DETECTION TECHNOLOGIES, IMPLEMENTATION STRATEGIES AND COMMERCIAL OPPORTUNITIES, 2005, 1 : 129 - 142
[33] Design and fabrication of integrated micro ammonia analysis system (IMAAS) with micro reactor and in-plane type optical detector using Berthelot reaction and micro fluidic devices
Park, JS
Park, KB
Shin, KS
Park, HD
Park, SJ
Song, YH
Kim, MC
Kim, JR
Transducers '05, Digest of Technical Papers, Vols 1 and 2, 2005, : 1828 - 1831
[34] Rapid prototyping of micro/nano poly (methyl methacrylate) fluidic systems using proton beam writing
Shao, P. G.
van Kan, J. A.
Wang, L. P.
Ansari, K.
Bettiol, A. A.
Watt, F.
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, 2007, 260 (01): : 362 - 365
[35] Nanofabrication of nano pattern and micro-devices using contact/proximity lithography
Ting, YC
Shy, SL
Lee, MC
Dai, BT
PHOTOMASK AND NEXT GENERATION LITHOGRAPHY MASK TECHNOLOGY XI, 2004, 5446 : 535 - 541
[36] Nano-to-micro self-assembly using shear flow devices
Shih, CY
Zheng, SY
Meng, E
Tai, YC
Liu, Y
Stoddart, JF
MEMS 2004: 17TH IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS, TECHNICAL DIGEST, 2004, : 422 - 425
[37] Simple Fabrication of Micromixer Based on Non-Equilibrium Electrokinetics in Micro/Nano Hybrid Fluidic System
Yu, Samuel
Kim, Sun Min
TRANSACTIONS OF THE KOREAN SOCIETY OF MECHANICAL ENGINEERS B, 2011, 35 (04) : 385 - 390
[38] Development of minimally invasive medical devices using micro/nano machining technology
Seimitsu Kogaku Kaishi, 2008, 11 (1139-1142):
[39] NOVEL PATTERNING TECHNOLOGY USING AIR-PRESSURE DISPENSER FOR FABRICATING MICRO-FLUIDIC DEVICES
Horiuchi, Toshiyuki
Otsuka, Shinichiro
Ozaki, Miyu
Ando, Ryota
Hiraki, Kazunari
BIODEVICES 2011, 2011, : 114 - 119
[40] Increasing Optical Path Lengths in Micro-Fluidic Devices Using a Multi-Pass Cell
Argueta-Diaz, Victor
Owens, Mckenna
Al Ramadan, Ahmed
MICROMACHINES, 2024, 15 (07)

← 1 2 3 4 5 →