Electrokinetic Biomolecule Preconcentration Using Xurography-Based Micro-Nano-Micro Fluidic Devices

被引：28

作者：

Yuan, Xichen ^{[1
]}

Renaud, Louis ^{[1
]}

Audry, Marie-Charlotte ^{[1
]}

Kleimann, Pascal ^{[1
]}

机构：

[1] Univ Lyon 1, CNRS, INL UMR5270, F-69622 Villeurbanne, France

来源：

ANALYTICAL CHEMISTRY | 2015年 / 87卷 / 17期

关键词：

CONCENTRATION POLARIZATION; NANOPOROUS MEMBRANES; TRANSPORT PHENOMENA; SAMPLE STACKING; ELECTROPHORESIS; PROPAGATION; SEPARATION; PROTEINS; ASSAY;

D O I：

10.1021/acs.analchem.5b01352

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In this paper we introduce a low cost rapid prototyping framework for designing Micro-Nano-Micro (MNM) fluidic preconcentration device based on ion concentration polarization (ICP) phenomenon. Xurography-based microchannels are separated by a strip of ion perm-selective Nafion membrane which plays the role of nanofluidic potential barrier for the negatively charged molecules. As a result, by using this rapid and inexpensive fabrication technique, it is possible to get preconcentration plugs as high as 5000 fold with an original symmetric electroosmotic flow (EOF) condition. Due to its simplicity and performance, this device could be implemented in various bioanalysis systems.

引用

页码：8695 / 8701

页数：7

共 50 条

[21] RAPID BACTERIA DETECTION IN WATER BASED ON MICRO/NANO DEVICES
Li, Mingxiao
Huang, Chengjun
Wang, Hui
Mao, Haiyang
Li, Li
Zhao, Yang
2017 19TH INTERNATIONAL CONFERENCE ON SOLID-STATE SENSORS, ACTUATORS AND MICROSYSTEMS (TRANSDUCERS), 2017, : 1570 - 1572
[22] Disposable digital micro-fluidic system using surface acoustic wave devices
Kondoh, Jun
Toyoizumi, Hitoshi
Sugita, Takaaki
INTERNATIONAL CONGRESS ON ULTRASONICS (GDANSK 2011), 2012, 1433 : 267 - 270
[23] Measurements of blood coagulation using digital micro-fluidic system based on surface acoustic wave devices
Kondoh, Jun
Ohashi, Noriyuki
2015 INTERNATIONAL CONFERENCE QUALITY IN RESEARCH (QIR), 2015, : 19 - 22
[24] Manufacture of Micro Fluidic Devices by Laser Welding using Thermal Transfer Printing Techniques
Klein, R.
Klein, K. F.
Tobisch, T.
Thoelken, D.
Belz, M.
OPTICAL FIBERS AND SENSORS FOR MEDICAL DIAGNOSTICS AND TREATMENT APPLICATIONS XVI, 2016, 9702
[25] Analysis of fluid flow through micro-fluidic devices using characteristic-based-split procedure
Celik, Bayram
Edis, Firat Oguz
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN FLUIDS, 2006, 51 (9-10) : 1041 - 1057
[26] Fabrication of micro/nano fluidic channels by nanoimprint lithography and bonding using SU-8
Yang, Rong
Lu, Bing-Rui
Wan, Jing
Xie, Shen-Qi
Chen, Yifang
Huq, Ejaz.
Qu, Xin-Ping
Liu, Ran
MICROELECTRONIC ENGINEERING, 2009, 86 (4-6) : 1379 - 1381
[27] Recent Progress of Micro/Nano Photonic Devices Based on Chalcogenide Glasses
Jian, Jialing
Ye, Yuting
Li, Junying
Shi, Yilin
Sun, Chunlei
Ma, Hui
Wu, Jianghong
Luo, Ye
Lin, Hongtao
Li, Lan
Kuei Suan Jen Hsueh Pao/Journal of the Chinese Ceramic Society, 2021, 49 (12): : 2676 - 2690
[28] Micro/Nano Energy Storage Devices Based on Composite Electrode Materials
Niu, Yanqi
Shang, Deyong
Li, Zhanping
NANOMATERIALS, 2022, 12 (13)
[29] Active cooling of integrated circuits and optoelectronic devices using a micro configured thermoelectric and fluidic system
Yu, Enchao
Wang, DeMing
Kim, Sura
Przekwas, Andrzej
2000, IEEE, Piscataway, NJ, United States (02):
[30] Laser welding of polymer micro-fluidic devices using novel diode laser sources
Hoult, AP
FOURTH INTERNATIONAL SYMPOSIUM ON LASER PRECISION MICROFABRICATION, 2003, 5063 : 308 - 313

← 1 2 3 4 5 →