Bromelain inhibits SARS-CoV-2 infection via targeting ACE-2, TMPRSS2, and spike protein

被引：18

作者：

Sagar, Satish ^{[1
]}

Rathinavel, Ashok Kumar ^{[1
]}

Lutz, William E. ^{[1
]}

Struble, Lucas R. ^{[1
]}

Khurana, Surender ^{[2
]}

Schnaubelt, Andy T. ^{[3
]}

Mishra, Nitish Kumar ^{[4
]}

Guda, Chittibabu ^{[4
,5
]}

Palermo, Nicholas Y. ^{[6
]}

Broadhurst, Mara J. ^{[3
]}

Hoffmann, Tobias ^{[7
]}

Bayles, Kenneth W. ^{[3
]}

Reid, St. Patrick M. ^{[3
]}

Borgstahl, Gloria E. O. ^{[7
]}

Radhakrishnan, Prakash ^{[3
]}

机构：

[1] Univ Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USA

[2] US FDA, Ctr Biol Evaluat & Res CBER, Div Viral Prod, Silver Spring, MD USA

[3] Univ Nebraska Med Ctr, Dept Pathol & Microbiol, Omaha, NE 68198 USA

[4] Univ Nebraska Med Ctr, Dept Genet Cell Biol & Anat, Omaha, NE USA

[5] Univ Nebraska Med Ctr, Fred & Pamela Buffett Canc Ctr, Omaha, NE USA

[6] Univ Nebraska Med Ctr, Computat Chem Core, Omaha, NE USA

[7] Robert Koch Inst, Adv Light & Electron Microscopy, Ctr Biol Threats & Special Pathogens 4 ZBS 4, Berlin, Germany

来源：

CLINICAL AND TRANSLATIONAL MEDICINE | 2021年 / 11卷 / 02期

关键词：

D O I：

10.1002/ctm2.281

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页数：6

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