68Ga-Pentixafor PET/CT May Fail to Detect Recurrent Multiple Myeloma with Extramedullary Disease

被引：1

作者：

Pan, Qingqing ^{[1
,2
,3
]}

Luo, Yaping ^{[1
,2
,3
]}

Cao, Xinxin ^{[2
,4
]}

Li, Jian ^{[2
,4
]}

Li, Fang ^{[1
,2
,3
]}

机构：

[1] Chinese Acad Med Sci, Dept Nucl Med, Beijing 100730, Peoples R China

[2] Peking Union Med Coll Hosp, Beijing 100730, Peoples R China

[3] Beijing Key Lab Mol Targeted Diag & Therapy Nucl M, Beijing 100730, Peoples R China

[4] Chinese Acad Med Sci, Dept Hematol, Beijing 100730, Peoples R China

来源：

DIAGNOSTICS | 2023年 / 13卷 / 05期

基金：

北京市自然科学基金;

关键词：

multiple myeloma; extramedullary disease; Ga-68-Pentixafor; PET/CT; RECEPTOR CXCR4 EXPRESSION; MODEL;

D O I：

10.3390/diagnostics13050871

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Two patients with a history of multiple myeloma experienced a recurrence of the disease.F-18-FDG PET/CT revealed prominent extramedullary disease as well as multi-foci in the bone marrow, both with increased FDG uptake. However, on Ga-68-Pentixafor PET/CT, all the myeloma lesions showed significantly lower tracer uptake in comparison with F-18-FDG PET. This false-negative result of recurrent multiple myeloma with extramedullary disease may be a potential limitation of Ga-68-Pentixafor in assessing multiple myeloma.

引用

页数：4

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