68Ga-Pentixafor PET/CT May Fail to Detect Recurrent Multiple Myeloma with Extramedullary Disease

被引：1
|
作者：
Pan, Qingqing [1 ,2 ,3 ]
Luo, Yaping [1 ,2 ,3 ]
Cao, Xinxin [2 ,4 ]
Li, Jian [2 ,4 ]
Li, Fang [1 ,2 ,3 ]
机构：
[1] Chinese Acad Med Sci, Dept Nucl Med, Beijing 100730, Peoples R China
[2] Peking Union Med Coll Hosp, Beijing 100730, Peoples R China
[3] Beijing Key Lab Mol Targeted Diag & Therapy Nucl M, Beijing 100730, Peoples R China
[4] Chinese Acad Med Sci, Dept Hematol, Beijing 100730, Peoples R China
来源：
DIAGNOSTICS | 2023年 / 13卷 / 05期
基金：
北京市自然科学基金;
关键词：
multiple myeloma; extramedullary disease; Ga-68-Pentixafor; PET/CT; RECEPTOR CXCR4 EXPRESSION; MODEL;
D O I：
10.3390/diagnostics13050871
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Two patients with a history of multiple myeloma experienced a recurrence of the disease.F-18-FDG PET/CT revealed prominent extramedullary disease as well as multi-foci in the bone marrow, both with increased FDG uptake. However, on Ga-68-Pentixafor PET/CT, all the myeloma lesions showed significantly lower tracer uptake in comparison with F-18-FDG PET. This false-negative result of recurrent multiple myeloma with extramedullary disease may be a potential limitation of Ga-68-Pentixafor in assessing multiple myeloma.
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页数：4
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