Multifactorial epigenomic profiling of six chromatin states in single cells

被引：0

作者：

Lochs, Silke J. A. ^{[1
]}

Kind, Jop ^{[1
]}

机构：

[1] Hubrecht Inst, Utrecht, Netherlands

来源：

NATURE METHODS | 2024年 / 21卷 / 01期

关键词：

D O I：

10.1038/s41592-023-02091-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We developed MAbID, a method for combined genomic profiling of histone modifications and chromatin-binding proteins in single cells, enabling researchers to study the interconnectivity between gene-regulatory mechanisms. We demonstrated MAbID's implementation in profiling multifactorial changes in chromatin signatures during in vitro neural differentiation and in primary mouse bone marrow tissue.

引用

页码：20 / 21

页数：2

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