Multifactorial epigenomic profiling of six chromatin states in single cells

被引：0
|
作者：
Lochs, Silke J. A. [1 ]
Kind, Jop [1 ]
机构：
[1] Hubrecht Inst, Utrecht, Netherlands
来源：
NATURE METHODS | 2024年 / 21卷 / 01期
关键词：
D O I：
10.1038/s41592-023-02091-8
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We developed MAbID, a method for combined genomic profiling of histone modifications and chromatin-binding proteins in single cells, enabling researchers to study the interconnectivity between gene-regulatory mechanisms. We demonstrated MAbID's implementation in profiling multifactorial changes in chromatin signatures during in vitro neural differentiation and in primary mouse bone marrow tissue.
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页码：20 / 21
页数：2
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