Idiopathic Hypereosinophilic Syndrome Presenting with Recalcitrant Oral and Genital Ulcers Responding Well to Thalidomide

被引：0
|
作者：
Srinivas, Sahana M. [1 ,3 ]
Chebbi, Pooja G. [2 ]
Shivappa, Sanjay K. [1 ]
机构：
[1] Indira Gandhi Inst Child Hlth, Dept Pediat Dermatol, Bengaluru, Karnataka, India
[2] Indira Gandhi Inst Child Hlth, Dept Pediat Med, Bengaluru, Karnataka, India
[3] Indira Gandhi Inst Child Hlth, Dept Pediat Dermatol, Bengaluru 560001, Karnataka, India
来源：
INDIAN DERMATOLOGY ONLINE JOURNAL | 2023年 / 14卷 / 05期
关键词：
Hypereosinophilic syndrome; idiopathic; mucosal ulcers; recurrent;
D O I：
10.4103/idoj.idoj_632_22
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Hypereosinophilic syndrome is a myeloproliferative disorder characterized by abnormal accumulation of eosinophils in the blood or peripheral tissues. It is uncommonly seen in children. We describe a 14-year-old girl diagnosed with idiopathic hypereosinophilic syndrome presenting with recurrent, painful oral and genital ulcers, hepatosplenomegaly along with consistently high eosinophil count and leucocytosis. Genetic studies showed negative for FIPIL-PDGFRA fusion gene. Mucosal ulcers were recalcitrant to conventional therapy and responded well to thalidomide.
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收藏
页码：676 / 678
页数：3
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