Idiopathic Hypereosinophilic Syndrome Presenting with Recalcitrant Oral and Genital Ulcers Responding Well to Thalidomide

被引：0
|
作者：
Srinivas, Sahana M. [1 ,3 ]
Chebbi, Pooja G. [2 ]
Shivappa, Sanjay K. [1 ]
机构：
[1] Indira Gandhi Inst Child Hlth, Dept Pediat Dermatol, Bengaluru, Karnataka, India
[2] Indira Gandhi Inst Child Hlth, Dept Pediat Med, Bengaluru, Karnataka, India
[3] Indira Gandhi Inst Child Hlth, Dept Pediat Dermatol, Bengaluru 560001, Karnataka, India
来源：
INDIAN DERMATOLOGY ONLINE JOURNAL | 2023年 / 14卷 / 05期
关键词：
Hypereosinophilic syndrome; idiopathic; mucosal ulcers; recurrent;
D O I：
10.4103/idoj.idoj_632_22
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Hypereosinophilic syndrome is a myeloproliferative disorder characterized by abnormal accumulation of eosinophils in the blood or peripheral tissues. It is uncommonly seen in children. We describe a 14-year-old girl diagnosed with idiopathic hypereosinophilic syndrome presenting with recurrent, painful oral and genital ulcers, hepatosplenomegaly along with consistently high eosinophil count and leucocytosis. Genetic studies showed negative for FIPIL-PDGFRA fusion gene. Mucosal ulcers were recalcitrant to conventional therapy and responded well to thalidomide.
引用
收藏
页码：676 / 678
页数：3
相关论文
共 48 条
  • [31] A Diagnosis of Idiopathic Hypereosinophilic Syndrome With Skin Involvement in a Patient Presenting With Lymphadenopathy and Rash
    Sekar, Nishanth
    Umakanth, Maheswaran
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2022, 14 (03)
  • [32] An unusual case of idiopathic hypereosinophilic syndrome presenting with myopericarditis and a polypoid cardiac mass
    Elalmis, Ozgl Ucar
    Mansuroglu, Candan
    Cicekcioglu, Hulya
    Karagoz, Ahmet
    TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, 2014, 42 (03): : 281 - 284
  • [33] Thalidomide for the treatment of acquired immunodeficiency syndrome-associated refractory oral ulcers
    Dios, PD
    Sopeña, B
    Cameselle, J
    Butrón, M
    Crespo, M
    Ocampo, A
    ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2000, 126 (01) : 89 - 92
  • [34] Vasculitis and oral and genital ulcers:: Behcet's syndrome or HIV infection?
    Olivé, A
    Fuente, MJ
    Veny, A
    Romeu, J
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 1999, 17 (01) : 124 - 124
  • [35] Two cases with hypereosinophilic syndrome shown with real-time PCR and responding well to imatinib treatment
    Nur Selvi
    Burçin Tezcanlı Kaymaz
    Handan Haydaroğlu Şahin
    Mustafa Pehlivan
    Çağdaş Aktan
    Ayşegül Dalmızrak
    Ezgi İnalpolat
    Buket Kosova
    Mehmet Yılmaz
    Vahap Okan
    Güray Saydam
    Molecular Biology Reports, 2013, 40 : 1591 - 1597
  • [36] Two cases with hypereosinophilic syndrome shown with real-time PCR and responding well to imatinib treatment
    Selvi, Nur
    Kaymaz, Burcin Tezcanli
    Sahin, Handan Haydaroglu
    Pehlivan, Mustafa
    Aktan, Cagdas
    Dalmizrak, Aysegul
    Inalpolat, Ezgi
    Kosova, Buket
    Yilmaz, Mehmet
    Okan, Vahap
    Saydam, Guray
    MOLECULAR BIOLOGY REPORTS, 2013, 40 (02) : 1591 - 1597
  • [37] Pemphigus Vegetans Presenting as Serpiginous Oral, Esophageal and Genital Mucosal Ulcers Undiagnosed for 3 Years
    Hadlaq, E.
    Al Bagieh, H.
    Qannam, A.
    Bello, I. O.
    NIGERIAN JOURNAL OF CLINICAL PRACTICE, 2018, 21 (09) : 1238 - 1241
  • [38] 17 YEAR-OLD FEMALE WITH IDIOPATHIC HYPEREOSINOPHILIC SYNDROME PRESENTING AS ANGIOEDEMA AND EOSINOPHILIC PLEURAL EFFUSIONS
    Stone, M.
    Eisenberg, R.
    Shliozberg, J.
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2017, 119 (05) : S48 - S48
  • [39] INVOLVEMENT OF THE NERVOUS SYSTEM IN RELAPSING UVEITIS WITH RECURRENT GENITAL AND ORAL ULCERS (BEHCETS SYNDROME)
    HERRMANN, C
    AMA ARCHIVES OF NEUROLOGY AND PSYCHIATRY, 1953, 69 (03): : 399 - 400
  • [40] NERVOUS SYSTEM INVOLVEMENT IN RELAPSING UVEITIS WITH RECURRENT GENITAL AND ORAL ULCERS (BEHCETS SYNDROME)
    HERRMANN, C
    JOURNAL OF NERVOUS AND MENTAL DISEASE, 1953, 117 (04) : 363 - 363
12345