DNA aptamer-immobilized magnetic nanoparticle having high selectivity, visual detection and rapid screening of Hg2+

被引:0
|
作者
Deepuppha, Nunthiya
Intakham, Peerapat
Rutnakornpituk, Metha
Rutnakornpituk, Boonjira [1 ,2 ]
机构
[1] Naresuan Univ, Fac Sci, Dept Chem, Phitsanulok 65000, Thailand
[2] Naresuan Univ, Fac Sci, Ctr Excellence Biomat, Phitsanulok 65000, Thailand
来源
关键词
Alginate; aptamer; Hg2+; magnetic nanoparticle; visual detection; PEPTIDE NUCLEIC-ACID; BISPHENOL-A; ASSAY; ADSORPTION; BIOSENSOR; MERCURY;
D O I
10.1080/25740881.2024.2307337
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
This novel nano-adsorbent offers high selectivity and rapid screening of Hg2+ through visual detection. The process involved coating the magnetic nanoparticle (MNP) with alginate, followed by immobilization of a DNA aptamer specific to Hg2+, resulting in the formation of Apt@Alg@MNP. It was utilized as a nano-adsorbent for rapid screening tests to qualitatively detect Hg2+ on the particles by observing the color change in the Hg2+-adsorbed Apt@Alg@MNP dispersion. The nano-adsorbent exhibited high specificity toward Hg2+ and demonstrated strong anti-interference capability. It was successfully employed as a nano-adsorbent for the determination of Hg2+ in various real water samples. [GRAPHICS] .
引用
收藏
页码:844 / 856
页数:13
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