DNA aptamer-immobilized magnetic nanoparticle having high selectivity, visual detection and rapid screening of Hg2+

被引：0

作者：

Deepuppha, Nunthiya

Intakham, Peerapat

Rutnakornpituk, Metha

Rutnakornpituk, Boonjira ^{[1
,2
]}

机构：

[1] Naresuan Univ, Fac Sci, Dept Chem, Phitsanulok 65000, Thailand

[2] Naresuan Univ, Fac Sci, Ctr Excellence Biomat, Phitsanulok 65000, Thailand

来源：

POLYMER-PLASTICS TECHNOLOGY AND MATERIALS | 2024年 / 63卷 / 07期

关键词：

Alginate; aptamer; Hg2+; magnetic nanoparticle; visual detection; PEPTIDE NUCLEIC-ACID; BISPHENOL-A; ASSAY; ADSORPTION; BIOSENSOR; MERCURY;

D O I：

10.1080/25740881.2024.2307337

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

This novel nano-adsorbent offers high selectivity and rapid screening of Hg2+ through visual detection. The process involved coating the magnetic nanoparticle (MNP) with alginate, followed by immobilization of a DNA aptamer specific to Hg2+, resulting in the formation of Apt@Alg@MNP. It was utilized as a nano-adsorbent for rapid screening tests to qualitatively detect Hg2+ on the particles by observing the color change in the Hg2+-adsorbed Apt@Alg@MNP dispersion. The nano-adsorbent exhibited high specificity toward Hg2+ and demonstrated strong anti-interference capability. It was successfully employed as a nano-adsorbent for the determination of Hg2+ in various real water samples. [GRAPHICS] .

引用

页码：844 / 856

页数：13

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