DNA aptamer-immobilized magnetic nanoparticle having high selectivity, visual detection and rapid screening of Hg2+

被引:0
|
作者
Deepuppha, Nunthiya
Intakham, Peerapat
Rutnakornpituk, Metha
Rutnakornpituk, Boonjira [1 ,2 ]
机构
[1] Naresuan Univ, Fac Sci, Dept Chem, Phitsanulok 65000, Thailand
[2] Naresuan Univ, Fac Sci, Ctr Excellence Biomat, Phitsanulok 65000, Thailand
来源
关键词
Alginate; aptamer; Hg2+; magnetic nanoparticle; visual detection; PEPTIDE NUCLEIC-ACID; BISPHENOL-A; ASSAY; ADSORPTION; BIOSENSOR; MERCURY;
D O I
10.1080/25740881.2024.2307337
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
This novel nano-adsorbent offers high selectivity and rapid screening of Hg2+ through visual detection. The process involved coating the magnetic nanoparticle (MNP) with alginate, followed by immobilization of a DNA aptamer specific to Hg2+, resulting in the formation of Apt@Alg@MNP. It was utilized as a nano-adsorbent for rapid screening tests to qualitatively detect Hg2+ on the particles by observing the color change in the Hg2+-adsorbed Apt@Alg@MNP dispersion. The nano-adsorbent exhibited high specificity toward Hg2+ and demonstrated strong anti-interference capability. It was successfully employed as a nano-adsorbent for the determination of Hg2+ in various real water samples. [GRAPHICS] .
引用
收藏
页码:844 / 856
页数:13
相关论文
共 50 条
  • [11] Autocatalytic DNA circuit for Hg2+ detection with high sensitivity and selectivity based on exonuclease III and G-quadruplex DNAzyme
    Zhou, Danhua
    Zeng, Lingwen
    Pan, Jiafeng
    Li, Qiong
    Chen, Junhua
    TALANTA, 2020, 207
  • [12] Phenazine-based colorimetric and fluorometric probes for rapid recognizing of Hg2+ with high sensitivity and selectivity
    Zhou, Haitao
    Sun, Lu
    Chen, Wei
    Tian, Guojian
    Chen, Yi
    Li, Yiru
    Su, Jianhua
    TETRAHEDRON, 2016, 72 (18) : 2300 - 2305
  • [13] DNA stabilized silver nanoclusters for ratiometric and visual detection of Hg2+ and its immobilization in hydrogels
    MacLean, James L.
    Morishita, Kiyoshi
    Liu, Juewen
    BIOSENSORS & BIOELECTRONICS, 2013, 48 : 82 - 86
  • [14] Visual detection of cyclobutane pyrimidine dimer DNA damage lesions by Hg2+ and carbon dots
    Singh, Seema
    Singh, Manoj K.
    Das, Prolay
    ANALYTICA CHIMICA ACTA, 2018, 1016 : 49 - 58
  • [15] A Simple and Rapid Resonance Scattering Spectral Method for Detection of Trace Hg2+ Using Aptamer-Nanogold as Probe
    Wen, Guiqing
    Liang, Aihui
    Fan, Yanyan
    Jiang, Zhiliang
    Jiang, Caina
    PLASMONICS, 2010, 5 (01) : 1 - 6
  • [16] A Simple and Rapid Resonance Scattering Spectral Method for Detection of Trace Hg2+ Using Aptamer-Nanogold as Probe
    Guiqing Wen
    Aihui Liang
    Yanyan Fan
    Zhiliang Jiang
    Caina Jiang
    Plasmonics, 2010, 5 : 1 - 6
  • [17] Impedimetric Immobilized DNA-Based Sensor for Simultaneous Detection of Pb2+, Ag+, and Hg2+
    Lin, Zhenzhen
    Li, Xiaohong
    Kraatz, Heinz-Bernhard
    ANALYTICAL CHEMISTRY, 2011, 83 (17) : 6896 - 6901
  • [18] Nuclease-resistant DNA aptamer on gold nanoparticles for the simultaneous detection of Pb2+ and Hg2+ in human serum
    Chung, Chan Ho
    Kim, Joong Hyun
    Jung, Juyeon
    Chung, Bong Hyun
    BIOSENSORS & BIOELECTRONICS, 2013, 41 : 827 - 832
  • [19] Rapid sequential detection of Hg2+ and biothiols by a probe DNA-MOF hybrid sensory system
    Huang, Nai-Han
    Li, Rong-Tian
    Fan, Cheng
    Wu, Ke-Yang
    Zhang, Zhe
    Chen, Jin-Xiang
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2019, 197
  • [20] One-step, room temperature, colorimetric detection of mercury (Hg2+) using DNA/nanoparticle conjugates
    Xue, Xuejia
    Wang, Feng
    Liu, Xiaogang
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (11) : 3244 - +