Two new sesquiterpene glycosides from the stems of Dendrobium henanense and their anti-inflammatory activity

被引：0

作者：

Wu, Si-Yu ^{[1
,2
]}

Jie, Hui-Yang ^{[1
]}

Wu, De-Ling ^{[1
,3
,4
]}

Qin, Shi-Hui ^{[1
]}

Tang, Xu ^{[1
]}

Wang, Ren-Zhong ^{[1
,4
]}

Xu, Feng-Qing ^{[1
,3
,4
]}

机构：

[1] Anhui Univ Chinese Med, Sch Pharm, Hefei, Peoples R China

[2] Taihe Cty Hosp Tradit Chinese Med, Taihe, Peoples R China

[3] Anhui Prov Key Lab New Mfg Technol Tradit Chinese, Hefei, Peoples R China

[4] Anhui Prov Key Lab Res & Dev Chinese Med, Hefei, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2024年

关键词：

Dendrobium henanense; terpenoids; NMR; anti-inflammatory; PICROTOXANE; COPACAMPHANE;

D O I：

10.1080/14786419.2024.2301739

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two new sesquiterpene glycosides, 8 alpha,12,15 beta-trihydroxycopacamphan-15-O-beta-D-glucopyranoside (1) and dendrobiumane C-11-O-beta-D-glucopyranoside (2), along with three known terpenoids (3-5) were isolated from the aerial stems of Dendrobium henanense. Their structures were elucidated based on NMR-spectroscopic and HR-MS analyses. All compounds could reduce the levels of NO, TNF-alpha and IL-1 beta in LPS-induced RAW264.7 cells with IC50 values ranging from 10.37 to 34.55 mu M.

引用

页数：6

共 50 条

[31] New compounds from the stems of Fissistigma acuminatissimum Merr. and their in vitro anti-inflammatory activity
Jin, Chen
Zhang, Ling
Yuan, Cheng-Jun
Liu, Yi
Liu, Hui-Zhen
Xu, Bo-Lun
Shu, Ji-Cheng
Zhang, Xiao-Yu
Wang, Si-Yi
Huang, Hui-Lian
NATURAL PRODUCT RESEARCH, 2023, 37 (04) : 551 - 559
[32] Phenylethanoid glycosides with anti-inflammatory activities from the stems of Cistanche deserticola cultured in Tarim desert
Nan, Ze-dong
Zeng, Ke-wu
Shi, She-po
Zhao, Ming-bo
Jiang, Yong
Tu, Peng-fei
FITOTERAPIA, 2013, 89 : 167 - 174
[33] Sesquiterpene glycosides from Dendrobium nobile and their chemotaxonomic significance
Tan, Daopeng
Qin, Lin
Wang, Jianmei
Gao, Chunxue
Lu, Yanliu
Yang, Zhou
He, Yuqi
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2023, 106
[34] New sesquiterpene derivatives and anti-inflammatory constituents from Pachira aquatica
Chen, J.
Cheng, L.
Liao, C.
Chung, M.
PLANTA MEDICA, 2011, 77 (12) : 1345 - 1345
[35] Two new compounds with anti-inflammatory activity from Alangium chinense
Yue, Yue-Dong
Xiang, Zhi-Nan
Chen, Jia-Chun
NATURAL PRODUCT RESEARCH, 2022, 36 (04) : 891 - 895
[36] Phenylpropanoid glycosides from Scrophularia scorodonia:: In vitro anti-inflammatory activity
Díaz, AM
Abad, MJ
Fernández, L
Silván, AM
De Santos, J
Bermejo, P
LIFE SCIENCES, 2004, 74 (20) : 2515 - 2526
[37] Phenylethanoid Glycosides from Lantana fucata with in Vitro Anti-inflammatory Activity
Juliao, Lisieux de Santana
Piccinelli, Anna Lisa
Marzocco, Stefania
Leitao, Suzana Guimaraes
Lotti, Cinzia
Autore, Giuseppina
Rastrelli, Luca
JOURNAL OF NATURAL PRODUCTS, 2009, 72 (08): : 1424 - 1428
[38] New monoterpene glycosides from the root cortex of Paeonia suffruticosa and their potential anti-inflammatory activity
Zhu, Xia
Fang, Ze-Hai
NATURAL PRODUCT RESEARCH, 2014, 28 (05) : 301 - 305
[39] Alkaloids from Dendrobium nobile and their anti-inflammatory activities
Xu, Zao-Yu
Wang, Chao-Fan
Li, Wen
Fu, Nan
Zhan, Rui
PHYTOCHEMISTRY LETTERS, 2025, 65 : 1 - 4
[40] Two new phenolic glycosides from the barks of Hydnocarpus annamensis and their anti-inflammatory and anti-oxidation activities
Shi, Hai-Ming
Wen, Jing
Jia, Cun-Qin
Jin, Wei
Zhang, Xiu-Feng
Yao, Zhi-Rong
Tu, Peng-Fei
PLANTA MEDICA, 2006, 72 (10) : 948 - 950

← 1 2 3 4 5 →