Synthesis,Structure and Biological Activity of Zn(II) Complex with Tris(benzimidazol-2-yl-methyl)amine Ligand

被引：0
|
作者：
刘小兰
赵茹
刘晓红
岳俊杰
尹宇新
孙云
孙命
机构：
[1] College of Chemistry and Life Science
[2] Tianjin Normal University
[3] Tianjin Normal University Tianjin 300074
[4] China
[5] China The Department of Ministry Logistics Port
[6] Naval Logistics Institute
[7] Tanggu
[8] Tianjin 300400
[9] China Key Laboratory of Bioorganic Phosphorous Chemistry
[10] Department of Chemistry
[11] Tsinghua University
[12] Beijing 100084
来源：
ChineseJournalofChemistry | 2004年 / 01期
关键词：
Zn(II) complex; tris(benzimidazol-2-yl-methyl)amine; superoxide dismutase (SOD); SOD model compound;
D O I：
暂无
中图分类号：
O627 [元素有机化合物];
学科分类号：
070303 ; 081704 ;
摘要：
A new Zn(II) mononuclear complex with tris(benzimidazol-2-yl-methyl)amine (NTB) was synthesized with stoichiometry of [Zn(NTB)NO3]NO3·DIPY·DMF (DIPY∶4,4’-dipyridyl). The complex was characterized by elemental analysis, UV and IR spectra. The crystal structure was determined by using X-ray diffraction analysis. The crystal structure indicates that four N atoms and one O atom coordinate to zinc ion to construct a distorted trigonal-dipyramid configuration. Three nonprotonated N atoms from imidazole groups are in the equatorial plane, one alkylamino N atom and one O atom from 3NO- in the axial directions. The biological activity assay shows that this complex presents certain biological activity by means of pyrogallol autoxidation and it can be called a model compound of superoxide dismutase (SOD).
引用
收藏
页码：75 / 79 +3
页数：6
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