Synthesis, crystal structure and DNA binding studies of Zn(II) complex with 1,3-bis(benzimidazol-2-yl)-2-oxapropane

被引：0
|
作者：
Zhou, QH [1 ]
Yang, P [1 ]
机构：
[1] Shanxi Univ, Inst Mol Sci, Educ Minist, Chem Biol & Mol Engn Lab, Taiyuan 030006, Peoples R China
来源：
ACTA CHIMICA SINICA | 2006年 / 64卷 / 08期
关键词：
DNA; Zn(II) complex; partial insertion;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A Zn(II) complex of L2Zn center dot(ClO4)(2)center dot 2CH(3)OH center dot H2O (L=1,3-bis(benzimidazol-2-yl)-2-oxapropane) has been synthesized and characterized by elemental analyses and X-ray single crystal diffraction. The Zn(II) environment in complex is distorted octahedron. The interaction of the complex with DNA has been investigated by using UV spectra, DNA melting, fluorescent spectra and viscosity. The results show that the Zn(II) complex can be partially intercalated into the double helix of DNA due to the planarity of the benzimidazole ring and the bulky structure of the complex.
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页码：793 / 798
页数：6
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