INTRAVESICAL MUC16 TARGETING CAR T CELLS FOR ORGAN-CONFINED BLADDER CANCERS

被引：0

作者：

Parwiz, Abrahimi ^{[1
]}

Jonathan, Khan ^{[1
]}

Alyssa, Duren-Lubanski ^{[1
]}

Winson, Cai ^{[1
]}

Yacine, Marouf ^{[1
]}

Jacob, Tallman ^{[1
]}

Bishoy, Faltas ^{[1
]}

Hikmat, Al Ahmadie ^{[1
]}

Olivier, Elemento ^{[1
]}

Benjamin, Hopkins ^{[1
]}

Douglas, Scherr ^{[1
]}

Renier, Brentjens ^{[1
]}

Jedd, Wolchok ^{[1
]}

Taha, Merghoub ^{[1
]}

机构：

[1] Weill Cornell Urol, New York, NY USA

来源：

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS | 2025年 / 43卷 / 03期

关键词：

D O I：

10.1016/j.urolonc.2024.12.242

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

243

引用

页数：2

共 46 条

[41] Multi-Antigen Targeting By Novel Combination of CAR-T Cells and hnCD16 Transgene, Yields in Complete Tumor Clearance Via Antibody Dependent Cellular Cytotoxicity
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[42] Multiplexed Engineered, Off-the-Shelf T Cells Carrying Three Tumor-Associated Antigen-Targeting Modalities: CAR plus Pan-Tumor Targeting TCR+CD16 Fc Receptor
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BLOOD, 2020, 136
[43] Antitumor effect of CAR-T cells targeting transmembrane tumor necrosis factor alpha combined with PD-1 mAb on breast cancers (vol 11, e003837, 2023)
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[44] Ligand-based, piggyBac-engineered CAR-T cells targeting EGFR are safe and effective against non-small cell lung cancers (vol 31, pg 1, 2023)
Chinsuwan, Thanyavi
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MOLECULAR THERAPY-ONCOLYTICS, 2023, 31
[45] TRI-MODAL CAR+TCR+HNCD16+ IPSC-DERIVED T CELLS CO-TARGETING SURFACE AND INTRACELLULAR/ NEOANTIGENS DEMONSTRATE ADDITIVE EFFECT ON OVERCOMING TUMOR HETEROGENEITY AND CANCER ESCAPE
Yang, Bi-Huei
Shirinbak, Soheila
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JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A315 - A315
[46] High-avidity BCMA CAR and high- affinity, non-cleavable CD16 Fc receptor incorporated in off-the-shelf CAR T cells promote multi-antigen targeting and durable anti-tumor cytotoxicity in the treatment of multiple myeloma
Reiser, John
O'Connor, Alison
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Markov, Spas
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Meza, Miguel
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Pan, Yijia
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CANCER RESEARCH, 2024, 84 (06)

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